XB-FEAT-487447

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mif

This is the community wiki page for the gene mif please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase


nomenclature changes

08/07/2017 Human name has changed for Entrez Gene: 4282. From macrophage migration inhibitory factor (glycosylation-inhibiting factor) to macrophage migration inhibitory factor


summary from NCBI

This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008]