XB-FEAT-5759170

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lsamp

This is the community wiki page for the gene lsamp please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

03.12.18 Human name has changed for Entrez Gene: 4045. From limbic system-associated membrane protein to limbic system associated membrane protein

Summary

This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neuronal surface glycoprotein. This protein may act as a selective homophilic adhesion molecule during axon guidance and neuronal growth in the developing limbic system. The encoded protein may also function as a tumor suppressor and may play a role in neuropsychiatric disorders. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]