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This is the community wiki page for the gene c1qa please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

02.25.20 name was changed from 'complement component 1, q subcomponent, A chain' to 'complement C1q A chain', following human nomenclature

Summary for HUMAN C1QA from NCBI

This gene encodes the A-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]