XB-FEAT-990636

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topbp1

This is the community wiki page for the gene topbp1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

08/07/2017 Human name has changed for Entrez Gene: 11073. From topoisomerase (DNA) II binding protein 1 to DNA topoisomerase II binding protein 1


summary from NCBI

This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq, Jul 2008]