XB-FEAT-22066184

h2ax

This is the Xenbase wiki page for the gene h2ax please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

08.23.2019

Human name has changed for Entrez Gene: 3014. From H2A histone family member X, gene 1 to H2A.X variant histone

Human symbol has changed for genepage ID: 22066184 From h2afx to h2ax

Human symbol has changed for Entrez Gene: 3014. From H2AFX.1 to H2AX

summary about human H2AX from NCBI

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015]