From XenWiki
Jump to navigation Jump to search


This is the community wiki page for the gene hsp90b1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

undated change by HGNC, probably in 2012 gene name and symbol were changed from glucose-regulated protein 94, grp94, to heat shock protein 90 beta family member 1, hsp90b1.

summary for human HSP90B1 from NCBI

This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15. [provided by RefSeq, Aug 2012]