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This is the community wiki page for the gene c1s please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

02.25.20 name changed from 'complement component 1, s subcomponent' to 'complement C1s' following human nomenclature

Summary for human C1S from NCBI

This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009]