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	<id>https://wiki.xenbase.org/xenwiki/index.php?action=history&amp;feed=atom&amp;title=2%2C2%CA%B9-Methylenebis%281%2C3-cyclohexanedione%29</id>
	<title>2,2ʹ-Methylenebis(1,3-cyclohexanedione) - Revision history</title>
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	<updated>2026-09-18T06:52:24Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wiki.xenbase.org/xenwiki/index.php?title=2,2%CA%B9-Methylenebis(1,3-cyclohexanedione)&amp;diff=48365&amp;oldid=prev</id>
		<title>imported&gt;Christina at 12:52, 19 May 2016</title>
		<link rel="alternate" type="text/html" href="https://wiki.xenbase.org/xenwiki/index.php?title=2,2%CA%B9-Methylenebis(1,3-cyclohexanedione)&amp;diff=48365&amp;oldid=prev"/>
		<updated>2016-05-19T12:52:35Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 12:52, 19 May 2016&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l1&quot;&gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;The Apoptosis Inhibitor 2,2ʹ-Methylenebis(1,3-cyclohexanedione) ( aka M50054 and  referenced under CAS 54135-60-3), controls the biological activity of Apoptosis. This small molecule/inhibitor is primarily used for Cancer applications, and in Xenopus has been used in amputation/regeneration studies. The anti-apoptotic effects have been shown to be attributable to inhibition of caspase-3 activation (IC50 = 334 nM), however it does not exhibit any direct inhibition of caspase-3 enzymatic activity.&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;The Apoptosis Inhibitor 2,2ʹ-Methylenebis(1,3-cyclohexanedione) ( aka M50054 and  referenced under CAS 54135-60-3), controls the biological activity of Apoptosis. This small molecule/inhibitor is primarily used for Cancer applications, and in Xenopus has been used in amputation/regeneration studies. The anti-apoptotic effects have been shown to be attributable to inhibition of caspase-3 activation (IC50 = 334 nM), however it does not exhibit any direct inhibition of caspase-3 enzymatic activity.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Chemical formua:C₁₃H₁₆O₄&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Supplier:  emd MIllipore: http://www.emdmillipore.com/US/en/product/Apoptosis-Inhibitor---CAS-54135-60-3---Calbiochem,EMD_BIO-178488#documentation&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>imported&gt;Christina</name></author>
	</entry>
	<entry>
		<id>https://wiki.xenbase.org/xenwiki/index.php?title=2,2%CA%B9-Methylenebis(1,3-cyclohexanedione)&amp;diff=48364&amp;oldid=prev</id>
		<title>imported&gt;Christina: Created page with &quot;The Apoptosis Inhibitor 2,2ʹ-Methylenebis(1,3-cyclohexanedione) ( aka M50054 and  referenced under CAS 54135-60-3), controls the biological activity of Apoptosis. This small ...&quot;</title>
		<link rel="alternate" type="text/html" href="https://wiki.xenbase.org/xenwiki/index.php?title=2,2%CA%B9-Methylenebis(1,3-cyclohexanedione)&amp;diff=48364&amp;oldid=prev"/>
		<updated>2016-05-19T12:49:45Z</updated>

		<summary type="html">&lt;p&gt;Created page with &amp;quot;The Apoptosis Inhibitor 2,2ʹ-Methylenebis(1,3-cyclohexanedione) ( aka M50054 and  referenced under CAS 54135-60-3), controls the biological activity of Apoptosis. This small ...&amp;quot;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;The Apoptosis Inhibitor 2,2ʹ-Methylenebis(1,3-cyclohexanedione) ( aka M50054 and  referenced under CAS 54135-60-3), controls the biological activity of Apoptosis. This small molecule/inhibitor is primarily used for Cancer applications, and in Xenopus has been used in amputation/regeneration studies. The anti-apoptotic effects have been shown to be attributable to inhibition of caspase-3 activation (IC50 = 334 nM), however it does not exhibit any direct inhibition of caspase-3 enzymatic activity.&lt;/div&gt;</summary>
		<author><name>imported&gt;Christina</name></author>
	</entry>
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