XB-FEAT-5763129 - Revision history

imported>Xenbase: /* ocm4.5 */

2021-07-08T20:44:31Z

ocm4.5

← Older revision		Revision as of 20:44, 8 July 2021
Line 1:		Line 1:
	=ocm4.5=		=ocm4.5=
	This is the community wiki page for the gene ''ocm'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase		This is the community wiki page for the gene ''ocm'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
			=nomenclature changes and synteny analysis=

	This gene renamed from ocm to ocm4.5 ~~on 7/1/2019~~		7/1/2019
			This gene renamed from ocm to ocm4.5

	This gene is part of the ocm locus which has 3 ancestral genes. Placental mammals only retained one, but humans duplicated with a chomosomal break exactly at the ocm gene, resulting in two closely related genes named OCM1 and OCM2. KAB unilaterally renamed this more ancestral gene as ocm4 to facilitate proper orthology between genes of species which retain more paralogs from the original locus than human has. These proposed gene names are under review by HGNC. However, this gene is not properly homologous to OCM1 nor OCM2 in human.		This gene is part of the ocm locus which has 3 ancestral genes. Placental mammals only retained one, but humans duplicated with a chomosomal break exactly at the ocm gene, resulting in two closely related genes named OCM1 and OCM2. KAB unilaterally renamed this more ancestral gene as ocm4 to facilitate proper orthology between genes of species which retain more paralogs from the original locus than human has. These proposed gene names are under review by HGNC. However, this gene is not properly homologous to OCM1 nor OCM2 in human.

	The ancestral locus, 5' to 3' is proposed to be OCM3 -> OCM4 -> OCM1		The ancestral locus, 5' to 3' is proposed to be OCM3 -> OCM4 -> OCM1
	Note that xenopus massively duplicated the OCM4 ~~paralogue~~.		Note that xenopus massively duplicated the OCM4 paralogs x10.

	This gene should not be renamed unless instructed by HGNC		This gene should not be renamed unless instructed by HGNC

			=synteny maps =
			Chicken: rsph10b> ccz1< loc#> ocm1< '''ocm4'''< ocm3< Loc< lmtk2>

			Human : rnf216< znf815p> OCM> rn7sl556p< ccz1> LOC< LOC>

			Xla.S ch9: ocm3> '''ocm4.1> ocm4.2> ocm4.3 > ocm4.5> ocm4.6>''' ocm1> ccz1b> rsph10b<

			Xla.L ch9_10: '''ocm4.1.L > ocm4.2.L > ocm4.3.L > ocm4.7.L > ocm4.8.L > ocm4.9.L > ocm4.10. L> ocm4.4.L > ocm4.5.L> ocm4.6>''' ocm1.L > ccz1.L> eif2ak1.L

			Xtr: rsph10b> ccz1< ocm1< '''ocm4.6'''< loc#< '''ocm4.5< ocm4.4<. ocm4.3<. ocm4.2< ocm4.1'''<

imported>KABurns: /* ocm4.5 */

2019-07-01T19:30:41Z

ocm4.5

← Older revision		Revision as of 19:30, 1 July 2019
Line 1:		Line 1:
	=~~ocm~~=		=ocm4.5=
	This is the community wiki page for the gene ''ocm'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase		This is the community wiki page for the gene ''ocm'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

			This gene renamed from ocm to ocm4.5 on 7/1/2019

			This gene is part of the ocm locus which has 3 ancestral genes. Placental mammals only retained one, but humans duplicated with a chomosomal break exactly at the ocm gene, resulting in two closely related genes named OCM1 and OCM2. KAB unilaterally renamed this more ancestral gene as ocm4 to facilitate proper orthology between genes of species which retain more paralogs from the original locus than human has. These proposed gene names are under review by HGNC. However, this gene is not properly homologous to OCM1 nor OCM2 in human.

			The ancestral locus, 5' to 3' is proposed to be OCM3 -> OCM4 -> OCM1
			Note that xenopus massively duplicated the OCM4 paralogue.

			This gene should not be renamed unless instructed by HGNC

imported>Xenbase gene generator at 12:00, 10 February 2010

2010-02-10T12:00:00Z

New page

=ocm=
This is the community wiki page for the gene ''ocm'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase