XB-FEAT-5768035 - Revision history

Christina: /* ocm4.3 */

2023-06-06T17:48:56Z

ocm4.3

← Older revision		Revision as of 17:48, 6 June 2023
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	This is the community wiki page for the gene ''ocm4.3'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase		This is the community wiki page for the gene ''ocm4.3'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

			=nomenclature changes=

	This gene was renamed from ''ocm.2'' to ''ocm4.3'' on 7/1/2019 by Xenbase curators (KAB)		This gene was renamed from ''ocm.2'' to ''ocm4.3'' on 7/1/2019 by Xenbase curators (KAB)

Christina: /* ocm.2 */

2023-06-06T17:48:40Z

ocm.2

← Older revision		Revision as of 17:48, 6 June 2023
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	=~~ocm~~.2=		=''ocm4.3''=
	This is the community wiki page for the gene ''~~ocm~~.2'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase		This is the community wiki page for the gene ''ocm4.3'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase


	This gene was renamed to ocm4.3 ~~from ocm.2~~ on 7/1/2019 by KAB		This gene was renamed from ''ocm.2'' to ''ocm4.3'' on 7/1/2019 by Xenbase curators (KAB)

	This gene is part of the ocm locus which has 3 ancestral genes. Placental mammals only retained one, but humans duplicated with a chomosomal break exactly at the ocm gene, resulting in two closely related genes named OCM1 and OCM2. KAB unilaterally renamed this more ancestral gene as ocm4 to facilitate proper orthology between genes of species which retain more paralogs from the original locus than human has. These proposed gene names are under review by HGNC. However, this gene is not properly homologous to OCM1 nor OCM2 in human.		This gene is part of the 'ocm' locus which has 3 ancestral genes.

	The ancestral locus, 5' to 3' is proposed to be OCM3 -> OCM4 -> OCM1 Note that ~~xenopus~~ massively duplicated the OCM4 paralogue.		Placental mammals only retained one, but humans duplicated with a chomosomal break exactly at the ocm gene, resulting in two closely related genes named OCM1 and OCM2.

			KAB unilaterally renamed this more ancestral gene as 'ocm4' to facilitate proper orthology between genes of species which retain more paralogs from the original locus than human has. These proposed gene names are under review by HGNC. However, this gene is not properly homologous to OCM1 nor OCM2 in human.

			The ancestral locus, 5' to 3' is proposed to be OCM3 -> OCM4 -> OCM1

			Note that Xenopus massively duplicated the OCM4 paralogue.

	This gene should not be renamed unless instructed by HGNC		This gene should not be renamed unless instructed by HGNC

			=synteny maps=
			Chicken: rsph10b> ccz1< loc#> ocm1< ocm4< ocm3< Loc< lmtk2>

			HUMAN : RNF216< ZNF815P> OCM> RN7SL556P< CCZ1> LOC< LOC>

			Xla.S ch9: ''ocm3> ocm4.1> ocm4.2> ocm4.3 > ocm4.5> ocm4.6> ocm1> ccz1b> rsph10b<''

			Xla.L ch9_10: ''ocm4.1.L > ocm4.2.L > ocm4.3.L > ocm4.7.L > ocm4.8.L > ocm4.9.L > ocm4.10. L> ocm4.4.L > ocm4.5.L> ocm4.6> ocm1.L > ccz1.L> eif2ak1.L''

			Xtr: ''rsph10b> ccz1< ocm1< ocm4.6< loc#< ocm4.5< ocm4.4<. ocm4.3<. ocm4.2< ocm4.1<''

imported>KABurns: /* ocm.2 */

2019-07-03T14:11:26Z

ocm.2

← Older revision		Revision as of 14:11, 3 July 2019
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	=ocm.2=		=ocm.2=
	This is the community wiki page for the gene ''ocm.2'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase		This is the community wiki page for the gene ''ocm.2'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase


			This gene was renamed to ocm4.3 from ocm.2 on 7/1/2019 by KAB

			This gene is part of the ocm locus which has 3 ancestral genes. Placental mammals only retained one, but humans duplicated with a chomosomal break exactly at the ocm gene, resulting in two closely related genes named OCM1 and OCM2. KAB unilaterally renamed this more ancestral gene as ocm4 to facilitate proper orthology between genes of species which retain more paralogs from the original locus than human has. These proposed gene names are under review by HGNC. However, this gene is not properly homologous to OCM1 nor OCM2 in human.

			The ancestral locus, 5' to 3' is proposed to be OCM3 -> OCM4 -> OCM1 Note that xenopus massively duplicated the OCM4 paralogue.

			This gene should not be renamed unless instructed by HGNC

imported>Xenbase gene generator at 12:00, 10 February 2010

2010-02-10T12:00:00Z

New page

=ocm.2=
This is the community wiki page for the gene ''ocm.2'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase