XB-FEAT-876668 - Revision history

Xenbase: /* nomenclature changes */

2023-10-02T18:04:10Z

nomenclature changes

← Older revision		Revision as of 18:04, 2 October 2023
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	=''col11a2''=		=''col11a2''=
	This is the community wiki page for the gene ''col11a2'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase		This is the community wiki page for the gene ''col11a2'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

			=summary for human COL11A2=

			This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Alternative splicing results in multiple transcript variants. A related pseudogene is located nearby on chromosome 6. [provided by RefSeq, Jul 2009]

	=nomenclature changes=		=nomenclature changes=

Xenbase: /* nomenclature changes */

2023-10-02T17:53:50Z

nomenclature changes

← Older revision		Revision as of 17:53, 2 October 2023
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	3OCT2023		3OCT2023
	~~Renamed gene, changing from col11a2p1 ro col11a2, removing ‘p1’ suffix as these are protein coding genes in Xenopus.~~

			Renamed gene, changing from ''col11a2p1'' to ''col11a2'', removing ‘p1’ suffix as these are protein coding genes in Xenopus.

			Humans have a true pc gene and an adjacent pseudogene on Chr6, flanked by BRD2 and RXRB.
			Xenopus tropicalis and X.laevis.S both have orthologous genes.

	Also, removed the human COL11A2P1 as ortholog from this gene page (done)		Also, removed the human COL11A2P1 as ortholog from this gene page (done)

Xenbase: /* Orthology and syntey */

2023-10-02T17:49:56Z

Orthology and syntey

← Older revision		Revision as of 17:49, 2 October 2023
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	Also, removed the human COL11A2P1 as ortholog from this gene page (done)		Also, removed the human COL11A2P1 as ortholog from this gene page (done)

	=Orthology and ~~syntey~~=		=Orthology and Synteny=

	Synteny shows that these genes are the true orthologs of human COL11A2, and therefore orthologs were moved from XB-GENEPAGE-12564498 to XB-GENEPAGE-876668		Synteny shows that these genes are the true orthologs of human COL11A2, and therefore orthologs were moved from XB-GENEPAGE-12564498 to XB-GENEPAGE-876668

	~~Xtrop~~ chr8:		Xtr.chr8:
	/// s''yngap1.L< LOC100486535(unch) cuta.L> phf1 < slc39a7 < hsd17b8> ring1>//// rxrb> '''col11a2(was col11a2p1- not a pseudogene)>''' mhc2-dcb< post12< tap1< tap2>'' (needed model updates on gene page)		/// s''yngap1.L< LOC100486535(unch) cuta.L> phf1 < slc39a7 < hsd17b8> ring1>//// rxrb> '''col11a2(was col11a2p1- not a pseudogene)>''' mhc2-dcb< post12< tap1< tap2>'' (needed model updates on gene page)

	Xla Chr8L: ''syngap1.L< cuta.L> phf1.L< slc39a7.L< ring1.L> ///LOC100137644(unch\|?hmga2)< rxrb.L> mhc-dab.L< mhc-daa.L> LOC108719087(p2rx7-like)< mhc2-dcb.L(eladab-a)< mhc2-dca.L> mhc2-dbb.L< LOC121397044(unch\|)< LOC121397045<. mhc2-dba''		Xla.Chr8L: ''syngap1.L< cuta.L> phf1.L< slc39a7.L< ring1.L> ///LOC100137644(unch\|?hmga2)< rxrb.L> mhc-dab.L< mhc-daa.L> LOC108719087(p2rx7-like)< mhc2-dcb.L(eladab-a)< mhc2-dca.L> mhc2-dbb.L< LOC121397044(unch\|)< LOC121397045<. mhc2-dba''

	Not present in Xlaevis L sub genome!		Not present in Xlaevis L sub genome!

	~~XlaChr8S~~:		Xla.Chr8S:
	''slc39a7.S < hsd17b8> ring1> rps18.S> wdr46.2> pfdn6.S> tapbp.S< zbtb22.S< LOC100126628(unch\|?hmga2)< rxrb.S> '''LOC108700220(col11a2.S)'''> brd.S< mhc2-dma.S''		''slc39a7.S < hsd17b8> ring1> rps18.S> wdr46.2> pfdn6.S> tapbp.S< zbtb22.S< LOC100126628(unch\|?hmga2)< rxrb.S> '''LOC108700220(col11a2.S)'''> brd.S< mhc2-dma.S''

	Human: chr6: BRD2> HLA-DOA< HLA-DPA1< HLA-DPB1> HLA-DPA2< COL11A2P1< '''COL11A2<''' RXRB< SLC39A7> RING1>		Human: chr6: BRD2> HLA-DOA< HLA-DPA1< HLA-DPB1> HLA-DPA2< COL11A2P1< '''COL11A2<''' RXRB< SLC39A7> RING1>

Xenbase: /* Orthology and syntey */

2023-10-02T17:48:54Z

Orthology and syntey

← Older revision		Revision as of 17:48, 2 October 2023
Line 18:		Line 18:

	Xtrop chr8:		Xtrop chr8:
	/// s''yngap1.L< LOC100486535(unch) cuta.L> phf1 < slc39a7 < hsd17b8> ring1>//// rxrb> '''col11a2(was col11a2p1- not a pseudogene)>''' mhc2-dcb< post12< tap1< tap2>'' (needed model updates on gene page)		/// s''yngap1.L< LOC100486535(unch) cuta.L> phf1 < slc39a7 < hsd17b8> ring1>//// rxrb> '''col11a2(was col11a2p1- not a pseudogene)>''' mhc2-dcb< post12< tap1< tap2>'' (needed model updates on gene page)

	Xla Chr8L: ''syngap1.L< cuta.L> phf1.L< slc39a7.L< ring1.L> ///LOC100137644(unch\|?hmga2)< rxrb.L> mhc-dab.L< mhc-daa.L> LOC108719087(p2rx7-like)< mhc2-dcb.L(eladab-a)< mhc2-dca.L> mhc2-dbb.L< LOC121397044(unch\|)< LOC121397045<. mhc2-dba''		Xla Chr8L: ''syngap1.L< cuta.L> phf1.L< slc39a7.L< ring1.L> ///LOC100137644(unch\|?hmga2)< rxrb.L> mhc-dab.L< mhc-daa.L> LOC108719087(p2rx7-like)< mhc2-dcb.L(eladab-a)< mhc2-dca.L> mhc2-dbb.L< LOC121397044(unch\|)< LOC121397045<. mhc2-dba''

Xenbase: /* nomenclature changes */

2023-10-02T17:48:42Z

nomenclature changes

← Older revision		Revision as of 17:48, 2 October 2023
Line 6:		Line 6:

	Human name has changed for Entrez Gene: 394214. From collagen, type XI, alpha 2 pseudogene 1 to collagen type XI alpha 2 pseudogene 1		Human name has changed for Entrez Gene: 394214. From collagen, type XI, alpha 2 pseudogene 1 to collagen type XI alpha 2 pseudogene 1

			3OCT2023
			Renamed gene, changing from col11a2p1 ro col11a2, removing ‘p1’ suffix as these are protein coding genes in Xenopus.


			Also, removed the human COL11A2P1 as ortholog from this gene page (done)

			=Orthology and syntey=

			Synteny shows that these genes are the true orthologs of human COL11A2, and therefore orthologs were moved from XB-GENEPAGE-12564498 to XB-GENEPAGE-876668

			Xtrop chr8:
			/// s''yngap1.L< LOC100486535(unch) cuta.L> phf1 < slc39a7 < hsd17b8> ring1>//// rxrb> '''col11a2(was col11a2p1- not a pseudogene)>''' mhc2-dcb< post12< tap1< tap2>'' (needed model updates on gene page)

			Xla Chr8L: ''syngap1.L< cuta.L> phf1.L< slc39a7.L< ring1.L> ///LOC100137644(unch\|?hmga2)< rxrb.L> mhc-dab.L< mhc-daa.L> LOC108719087(p2rx7-like)< mhc2-dcb.L(eladab-a)< mhc2-dca.L> mhc2-dbb.L< LOC121397044(unch\|)< LOC121397045<. mhc2-dba''

			Not present in Xlaevis L sub genome!

			XlaChr8S:
			''slc39a7.S < hsd17b8> ring1> rps18.S> wdr46.2> pfdn6.S> tapbp.S< zbtb22.S< LOC100126628(unch\|?hmga2)< rxrb.S> '''LOC108700220(col11a2.S)'''> brd.S< mhc2-dma.S''

			Human: chr6: BRD2> HLA-DOA< HLA-DPA1< HLA-DPB1> HLA-DPA2< COL11A2P1< '''COL11A2<''' RXRB< SLC39A7> RING1>

Xenbase: /* col11a2p */

2023-10-02T17:42:23Z

col11a2p

← Older revision		Revision as of 17:42, 2 October 2023
Line 1:		Line 1:
	=''~~col11a2p~~''=		=''col11a2''=
	This is the community wiki page for the gene ''~~col11a2p~~'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase		This is the community wiki page for the gene ''col11a2'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

	=nomenclature changes=		=nomenclature changes=

Xenbase: /* col11a2p */

2023-10-02T16:11:50Z

col11a2p

← Older revision		Revision as of 16:11, 2 October 2023
Line 1:		Line 1:
	=col11a2p=		=''col11a2p''=
	This is the community wiki page for the gene ''col11a2p'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase		This is the community wiki page for the gene ''col11a2p'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

imported>Xenbase at 18:16, 26 May 2017

2017-05-26T18:16:06Z

← Older revision		Revision as of 18:16, 26 May 2017
Line 1:		Line 1:
	=col11a2p=		=col11a2p=
	This is the community wiki page for the gene ''col11a2p'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase		This is the community wiki page for the gene ''col11a2p'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

			=nomenclature changes=
			04/22/ 2016

			Human name has changed for Entrez Gene: 394214. From collagen, type XI, alpha 2 pseudogene 1 to collagen type XI alpha 2 pseudogene 1

imported>Xenbase gene generator at 12:00, 10 February 2010

2010-02-10T12:00:00Z

New page

=col11a2p=
This is the community wiki page for the gene ''col11a2p'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase