XB-FEAT-492114

ido2

This is the community wiki page for the gene ido2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature updates

06MAY2026

Xenopus gene name and symbol has changed from ido1 indoleamine 2,3-dioxygenase 1, to ido2, indoleamine 2,3-dioxygenase 2 based on orthology prediction analsyis by NCBI.

orthology & synteny notes

06MAY2026

Note that IDO1 and IDO2 are adjacent, duplicated genes on Chrom 8 in human but Xenopus only has the single gene, now named ido2, on chr3/3L.

In humans, the enzymes encoded by IDO1 & IDO2 genes metabolize tryptophan in the kynurenine pathway.