XB-FEAT-1013383: Difference between revisions
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This is the community wiki page for the gene ''neil1'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase. | This is the community wiki page for the gene ''neil1'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase. | ||
= | =gene expression notes= | ||
neil1 is only expressed in very low levels of the embryo, and therefore there are no ISH images published or yet avavilable. Christoph | neil1 is only expressed in very low levels of the embryo, and therefore there are no ISH images published or yet avavilable. Christoph Niehrs works on the this gene, and has used MOs to knockout/down, with significant phenotypic effects. | ||
=NCBI summary= | =NCBI summary= | ||
This gene is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012] | This gene is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012] | ||
Latest revision as of 01:09, 30 June 2017
neil1
This is the community wiki page for the gene neil1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.
gene expression notes
neil1 is only expressed in very low levels of the embryo, and therefore there are no ISH images published or yet avavilable. Christoph Niehrs works on the this gene, and has used MOs to knockout/down, with significant phenotypic effects.
NCBI summary
This gene is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]