XB-FEAT-1016185: Difference between revisions
imported>Xenbase gene generator No edit summary |
imported>Xenbase |
||
| Line 1: | Line 1: | ||
=enpp2= | =enpp2= | ||
This is the community wiki page for the gene ''enpp2'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | This is the community wiki page for the gene ''enpp2'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | ||
summary from NCBI= | |||
The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008] | |||
Latest revision as of 07:12, 17 August 2017
enpp2
This is the community wiki page for the gene enpp2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
summary from NCBI=
The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008]