XB-FEAT-978041: Difference between revisions
imported>Xenbase |
imported>Xenbase |
||
| Line 10: | Line 10: | ||
Human name has changed for Entrez Gene: 55120. From Fanconi anemia complementation group L to FA complementation group L | Human name has changed for Entrez Gene: 55120. From Fanconi anemia complementation group L to FA complementation group L | ||
=summary from NCBI= | |||
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] | |||
Latest revision as of 10:26, 15 May 2018
fancl
This is the community wiki page for the gene fancl please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
nomenclature changes
01/12/2016
Human name has changed for Entrez Gene: 55120. From Fanconi anemia, complementation group L to Fanconi anemia complementation group L
05.14.2018
Human name has changed for Entrez Gene: 55120. From Fanconi anemia complementation group L to FA complementation group L
summary from NCBI
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]