XB-FEAT-6050068: Difference between revisions
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=grik2= | =grik2= | ||
This is the community wiki page for the gene ''grik2'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | This is the community wiki page for the gene ''grik2'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase. | ||
=summary from ncbi= | |||
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive cognitive disability *. [provided by RefSeq, Jul 2008] | |||
* including autism | |||
Latest revision as of 05:48, 31 May 2018
grik2
This is the community wiki page for the gene grik2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.
summary from ncbi
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive cognitive disability *. [provided by RefSeq, Jul 2008]
* including autism