XB-FEAT-486826: Difference between revisions
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= | =mrtfa= | ||
This is the community wiki page for the gene '' | This is the community wiki page for the gene ''mrtfa'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase. | ||
=Nomenclature changes= | |||
06.19.2018 | |||
Human symbol has changed for genepage ID: 486826 From mkl1 to mrtfa | |||
Human symbol has changed for Entrez Gene: 57591. From MKL1 to MRTFA | |||
Human name has changed for Entrez Gene: 57591. From megakaryoblastic leukemia (translocation) 1 to myocardin related transcription factor A | |||
=Summary from NCBI= | |||
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] | |||
Latest revision as of 08:52, 19 June 2018
mrtfa
This is the community wiki page for the gene mrtfa please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.
Nomenclature changes
06.19.2018
Human symbol has changed for genepage ID: 486826 From mkl1 to mrtfa
Human symbol has changed for Entrez Gene: 57591. From MKL1 to MRTFA
Human name has changed for Entrez Gene: 57591. From megakaryoblastic leukemia (translocation) 1 to myocardin related transcription factor A
Summary from NCBI
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]