XB-FEAT-983363: Difference between revisions
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=guf1= | =''guf1''= | ||
This is the community wiki page for the gene ''guf1'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | This is the community wiki page for the gene ''guf1'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | ||
=nomenclature changes= | |||
10.15.2020 | |||
Human name has changed for Entrez Gene: 60558. From GUF1 homolog, GTPase to GTP binding elongation factor GUF1 | |||
=summary from NCBI for human GUF1= | |||
This gene encodes a GTPase that triggers back-translocation of the elongating ribosome during mitochondrial protein synthesis. The protein contains a highly conserved C-terminal domain not found in other GTPases that facilitates tRNA binding. The encoded protein is thought to prevent misincorporation of amino acids in stressful, suboptimal conditions. An allelic variant in this gene has been associated with early infantile epileptic encephalopathy-40. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] | |||
Latest revision as of 12:22, 4 November 2020
guf1
This is the community wiki page for the gene guf1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
nomenclature changes
10.15.2020
Human name has changed for Entrez Gene: 60558. From GUF1 homolog, GTPase to GTP binding elongation factor GUF1
summary from NCBI for human GUF1
This gene encodes a GTPase that triggers back-translocation of the elongating ribosome during mitochondrial protein synthesis. The protein contains a highly conserved C-terminal domain not found in other GTPases that facilitates tRNA binding. The encoded protein is thought to prevent misincorporation of amino acids in stressful, suboptimal conditions. An allelic variant in this gene has been associated with early infantile epileptic encephalopathy-40. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]