XB-FEAT-922295: Difference between revisions
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=kirrel3= | =kirrel3= | ||
This is the community wiki page for the gene ''kirrel3'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | This is the community wiki page for the gene ''kirrel3'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | ||
=nomenclature changes= | |||
06/12/2017. | |||
Human name has changed for Entrez Gene: 84623. From kin of IRRE like 3 (Drosophila) to kirre like nephrin family adhesion molecule 3. | |||
=summary from NCBI= | |||
The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. Mutations in this gene are associated with mental retardation autosomal dominant type 4 (MRD4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] | |||
Latest revision as of 14:47, 15 June 2017
kirrel3
This is the community wiki page for the gene kirrel3 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
nomenclature changes
06/12/2017.
Human name has changed for Entrez Gene: 84623. From kin of IRRE like 3 (Drosophila) to kirre like nephrin family adhesion molecule 3.
summary from NCBI
The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. Mutations in this gene are associated with mental retardation autosomal dominant type 4 (MRD4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]