XB-FEAT-957567: Difference between revisions
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=bag1= | =bag1= | ||
This is the community wiki page for the gene ''bag1'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | This is the community wiki page for the gene ''bag1'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | ||
= NCBI Summary for human BAG1= | |||
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010] | |||
=nomenclature changes= | |||
10.18.2019 | |||
Human name has changed for Entrez Gene: 573. From BCL2 associated athanogene 1 to BAG cochaperone 1 | |||
Latest revision as of 08:46, 29 October 2019
bag1
This is the community wiki page for the gene bag1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
NCBI Summary for human BAG1
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010]
nomenclature changes
10.18.2019
Human name has changed for Entrez Gene: 573. From BCL2 associated athanogene 1 to BAG cochaperone 1