XB-FEAT-958792: Difference between revisions
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=cox17= | =cox17= | ||
This is the community wiki page for the gene ''cox17'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | This is the community wiki page for the gene ''cox17'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | ||
=Summary from NCBI= | |||
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13. [provided by RefSeq, Jul 2008]. | |||
=nomenclature changes= | |||
06.26.2018 | |||
Human name has changed for Entrez Gene: 10063. From COX17, cytochrome c oxidase copper chaperone to cytochrome c oxidase copper chaperone COX17 | |||
Latest revision as of 06:38, 26 June 2018
cox17
This is the community wiki page for the gene cox17 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
Summary from NCBI
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13. [provided by RefSeq, Jul 2008].
nomenclature changes
06.26.2018
Human name has changed for Entrez Gene: 10063. From COX17, cytochrome c oxidase copper chaperone to cytochrome c oxidase copper chaperone COX17