BAPTA-AM: Difference between revisions

From XenWiki
Jump to navigation Jump to search
imported>Kevin
Created page with "==Description== Selective calcium chelator that is the cell-permeable analog of BAPTA (Cat. No. 2786). Blocks hKv1.5, hKV11.1 (hERG) and hKv1.3 channels (Ki values are 1.23, 1..."
 
imported>Kevin
No edit summary
 
(2 intermediate revisions by the same user not shown)
Line 1: Line 1:
==Description==
==Description==
Selective calcium chelator that is the cell-permeable analog of BAPTA (Cat. No. 2786). Blocks hKv1.5, hKV11.1 (hERG) and hKv1.3 channels (Ki values are 1.23, 1.30 and 1.45 μM respectively). Displays antithrombotic activity in vitro.
Selective calcium chelator that is the cell-permeable analog of BAPTA (Cat. No. 2786). Blocks hKv1.5, hKV11.1 (hERG) and hKv1.3 channels (Ki values are 1.23, 1.30 and 1.45 μM respectively). Displays antithrombotic activity in vitro.
[[File:BAPTAAM.png]]
[[File:BAPTAAM.png|frame|right|Structure of BAPTA-AM, photo from Sigma-Aldrich]]


**Genes Affected
**Genes Affected
Line 18: Line 18:


==References==
==References==
*[https://pubchem.ncbi.nlm.nih.gov/compound/2293 PubChem]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=4661 Leclerc et al., 2003]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=4661 Leclerc et al., 2003]


>762 Xenbase articles contain a reference to BAPTA-AM according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
>762 Xenbase articles contain a reference to BAPTA-AM according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
*
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]

Latest revision as of 12:28, 2 June 2015

Description

Selective calcium chelator that is the cell-permeable analog of BAPTA (Cat. No. 2786). Blocks hKv1.5, hKV11.1 (hERG) and hKv1.3 channels (Ki values are 1.23, 1.30 and 1.45 μM respectively). Displays antithrombotic activity in vitro.

Structure of BAPTA-AM, photo from Sigma-Aldrich

Suppliers

Usage Notes

.4uM in .1x NAM

References

>762 Xenbase articles contain a reference to BAPTA-AM according to textpresso