MMP-2 inhibitor II: Difference between revisions

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Created page with "==Description== [[File:______|frame|right|_______ structure, photo from Sigma-Aldrich]] ==Genes Affected== ==Suppliers== *[http://www.xenbase.org/entry/ SORRYONLYALINKTOXENB..."
 
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==Description==
==Description==
[[File:______|frame|right|_______ structure, photo from Sigma-Aldrich]]
"An oxirane analog of SB-3CT, pMS (Cat. No. 444285) that acts as a selective, active site-binding, irreversible inhibitor of MMP-2 (Ki = 2.4 µM). Although less potent, it exhibits enhanced selectivity towards MMP-2 (Ki = 45 and 379 µM for MMP-1 and MMP-7, respectively) than SB-3CT, pMS."
*-EMD Millipore product description
[[File:MMP2_inhibitor_ii.png|frame|right| MMP-2 inhibitor II structure, photo from PubChem]]


==Genes Affected==
==Genes Affected==
*[http://www.xenbase.org/gene/showgene.do?method=display&geneId=482840 mmp2]


==Suppliers==
==Suppliers==
*[http://www.xenbase.org/entry/ SORRYONLYALINKTOXENBASE]
*[http://www.emdmillipore.com/US/en/product/MMP-2-Inhibitor-II---CAS-869577-51-5---Calbiochem,EMD_BIO-444286?isCountryEMD=yes&&attachments=CoA&bd=1 calbiochem 444286 is now EMD Millipore]


==Usage Notes==
==Usage Notes==


==References==
==References==
*[https://pubchem.ncbi.nlm.nih.gov/ Pubchem]
*[https://pubchem.ncbi.nlm.nih.gov/compound/15940371#section=Top Pubchem]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=__________ ____ et al., 2xxxx]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=49477 Iwao et al., 2015]


>___ Xenbase articles contain a reference to _____ according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
>Search for additional Xenbase articles referring to MMP-2 inhibitor II according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
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*
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]

Latest revision as of 10:48, 23 June 2015

Description

"An oxirane analog of SB-3CT, pMS (Cat. No. 444285) that acts as a selective, active site-binding, irreversible inhibitor of MMP-2 (Ki = 2.4 µM). Although less potent, it exhibits enhanced selectivity towards MMP-2 (Ki = 45 and 379 µM for MMP-1 and MMP-7, respectively) than SB-3CT, pMS."

  • -EMD Millipore product description
MMP-2 inhibitor II structure, photo from PubChem

Genes Affected

Suppliers

Usage Notes

References

>Search for additional Xenbase articles referring to MMP-2 inhibitor II according to textpresso