MMP-2 inhibitor II: Difference between revisions
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==Description== | ==Description== | ||
"An oxirane analog of SB-3CT, pMS (Cat. No. 444285) that acts as a selective, active site-binding, irreversible inhibitor of MMP-2 (Ki = 2.4 µM). Although less potent, it exhibits enhanced selectivity towards MMP-2 (Ki = 45 and 379 µM for MMP-1 and MMP-7, respectively) than SB-3CT, pMS." | |||
*-EMD Millipore product description | |||
[[File:MMP2_inhibitor_ii.png|frame|right| MMP-2 inhibitor II structure, photo from PubChem]] | [[File:MMP2_inhibitor_ii.png|frame|right| MMP-2 inhibitor II structure, photo from PubChem]] | ||
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==References== | ==References== | ||
*[https://pubchem.ncbi.nlm.nih.gov/ Pubchem] | *[https://pubchem.ncbi.nlm.nih.gov/compound/15940371#section=Top Pubchem] | ||
*[http://www.xenbase.org/literature/article.do?method=display&articleId=49477 Iwao et al., 2015] | *[http://www.xenbase.org/literature/article.do?method=display&articleId=49477 Iwao et al., 2015] | ||
Latest revision as of 10:48, 23 June 2015
Description
"An oxirane analog of SB-3CT, pMS (Cat. No. 444285) that acts as a selective, active site-binding, irreversible inhibitor of MMP-2 (Ki = 2.4 µM). Although less potent, it exhibits enhanced selectivity towards MMP-2 (Ki = 45 and 379 µM for MMP-1 and MMP-7, respectively) than SB-3CT, pMS."
- -EMD Millipore product description
Genes Affected
Suppliers
Usage Notes
References
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