Nicorandil: Difference between revisions
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imported>Kevin Created page with "==Description== [[File:______|frame|right|_______ structure, photo from Sigma-Aldrich]] ==Genes Affected== ==Suppliers== *[http://www.xenbase.org/entry/ SORRYONLYALINKTOXENB..." |
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==Description== | ==Description== | ||
[[File: | Nicorandil is a dual-action potassium channel opener that relaxes vascular smooth muscle through membrane hyperpolarization via increased transmembrane potassium conductance and increased intracellular concentration of cyclic GMP. | ||
[[File:nicorandil.png|frame|right|nicorandil structure, photo from pubchem]] | |||
==Genes Affected== | ==Genes Affected== | ||
==Suppliers== | ==Suppliers== | ||
*[ | *[https://pubchem.ncbi.nlm.nih.gov/compound/47528#section=Chemical-Vendors via pubChem] | ||
*Merck KgaA | |||
==Usage Notes== | ==Usage Notes== | ||
4.7uM from stock of 100mg/11mL of water + 1 mL of DMSO | |||
==References== | ==References== | ||
*[https://pubchem.ncbi.nlm.nih.gov/ Pubchem] | *[https://pubchem.ncbi.nlm.nih.gov/compound/47528 Pubchem] | ||
*[http://www.xenbase.org/literature/article.do?method=display&articleId= | *[http://www.xenbase.org/literature/article.do?method=display&articleId=6115 Cheng et al., 2002] | ||
> | >19 Xenbase articles contain a reference to nicorandil according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso] | ||
* | * | ||
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]] | *[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]] | ||
Latest revision as of 12:09, 20 December 2017
Description
Nicorandil is a dual-action potassium channel opener that relaxes vascular smooth muscle through membrane hyperpolarization via increased transmembrane potassium conductance and increased intracellular concentration of cyclic GMP.
Genes Affected
Suppliers
- via pubChem
- Merck KgaA
Usage Notes
4.7uM from stock of 100mg/11mL of water + 1 mL of DMSO
References
>19 Xenbase articles contain a reference to nicorandil according to textpresso