XB-FEAT-855696: Difference between revisions
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= | = ''ifnl3'' = | ||
This is the community wiki page for the gene '' | This is the community wiki page for the gene ''ifnl3'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | ||
=nomenclature changes= | |||
12May2023 | |||
Following human gen ename update, ''Xenopus'' gene name changed from ''il28b.1, interleukin 28B (interferon, lambda 3), gene 1'' to ''ifnl3, interferon lambda 3''. | |||
''il28b'' and ''il28b.1'' are recorded as legacy gene symbols | |||
=summary for human IFNL3 from NCBI= | |||
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008] | |||
Latest revision as of 07:15, 12 May 2023
ifnl3
This is the community wiki page for the gene ifnl3 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
nomenclature changes
12May2023
Following human gen ename update, Xenopus gene name changed from il28b.1, interleukin 28B (interferon, lambda 3), gene 1 to ifnl3, interferon lambda 3.
il28b and il28b.1 are recorded as legacy gene symbols
summary for human IFNL3 from NCBI
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]