Small Molecules for Xenopus Research: Difference between revisions
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*[[1,3-Dicyclohexylurea]] | *[[1,3-Dicyclohexylurea]] | ||
*[[11-cis retinal]] | *[[11-cis retinal]] | ||
*[[18alpha- | *[[18alpha-glycyrrhetinic acid]] | ||
*[[2'-deoxyadenosine]] | *[[2'-deoxyadenosine]] | ||
*[[2-APB]] | *[[2-APB]] | ||
| Line 19: | Line 19: | ||
*[[8-Pcpt-2-O-Me-cAMP-AM]] | *[[8-Pcpt-2-O-Me-cAMP-AM]] | ||
*[[activin]] | *[[activin]] | ||
*[[Adenosine, periodate oxidized]] | |||
*[[AG1296]] | *[[AG1296]] | ||
*[[AG1879]] | *[[AG1879]] | ||
*[[AGN193109]] | *[[AGN193109]] | ||
*[[alpha-amanitin]] | *[[alpha-amanitin]] | ||
*[[Alisertib]] | |||
*[[anandamide]] | *[[anandamide]] | ||
*[[AP-III-a4]] | *[[AP-III-a4]] | ||
*[[apelin]] | *[[apelin]] | ||
*[[aphidicolin]] | *[[aphidicolin]] | ||
*[[Aroclor 1254]] | |||
*[[Atrazine]] | |||
*[[AZD1480]] | *[[AZD1480]] | ||
*[[Bafilomycin A1]] | *[[Bafilomycin A1]] | ||
| Line 38: | Line 42: | ||
*[[bumetanide]] | *[[bumetanide]] | ||
*[[calcium ionophore]] | *[[calcium ionophore]] | ||
*[[canertinib]] | |||
*[[CGP54626 ]] | *[[CGP54626 ]] | ||
*[[Chelerythrine]] | *[[Chelerythrine]] | ||
*[[chenodeoxycholic acid]] | *[[chenodeoxycholic acid]] | ||
*[[chlorpromazine]] | |||
*[[chymostatin ]] | *[[chymostatin ]] | ||
*[[Citral]] | *[[Citral]] | ||
| Line 53: | Line 59: | ||
*[[D-AP5]] | *[[D-AP5]] | ||
*[[D-NAME]] | *[[D-NAME]] | ||
*[[deltamethrin]] | *[[deltamethrin]] | ||
*[[dexamethosone]] | *[[dexamethosone]] | ||
| Line 76: | Line 81: | ||
*[[heptanol]] | *[[heptanol]] | ||
*[[herbimycin A]] | *[[herbimycin A]] | ||
*[[Hh-Ag1.8]] | |||
*[[Hydroxyurea]] | *[[Hydroxyurea]] | ||
*[[IBMX]] | *[[IBMX]] | ||
| Line 81: | Line 87: | ||
*[[jasplakinolide]] | *[[jasplakinolide]] | ||
*[[6-B345TTQ]] | *[[6-B345TTQ]] | ||
*[[Ketamine]] | |||
*[[KT 5720]] | *[[KT 5720]] | ||
*[[L-NAME]] | *[[L-NAME]] | ||
| Line 87: | Line 94: | ||
*[[latrunculin B]] | *[[latrunculin B]] | ||
*[[LDN-193189]] | *[[LDN-193189]] | ||
*[[Leflunomide]] | |||
*[[leucovorin]] | *[[leucovorin]] | ||
*[[LiCl]] | *[[LiCl]] | ||
*[[Lovastatin]] | |||
*[[LY294002]] | *[[LY294002]] | ||
*[[m-3M3FBS]] | *[[m-3M3FBS]] | ||
| Line 114: | Line 123: | ||
*[[taxol|Paclitaxel]] | *[[taxol|Paclitaxel]] | ||
*[[phaclofen]] | *[[phaclofen]] | ||
*[[phenylthiourea|phenylthiourea (PTU)]] | |||
*[[Picropodophyllin]] | *[[Picropodophyllin]] | ||
*[[PMA]] | *[[PMA]] | ||
| Line 120: | Line 130: | ||
*[[Progesterone]] | *[[Progesterone]] | ||
*[[propylthiouracil]] | *[[propylthiouracil]] | ||
*[[psoralen]] | |||
*[[pyrimethamine]] | *[[pyrimethamine]] | ||
*[[quinpirole]] | *[[quinpirole]] | ||
| Line 132: | Line 143: | ||
*[[SB 203580]] | *[[SB 203580]] | ||
*[[SB431542]] | *[[SB431542]] | ||
*[[SB 505124]] | *[[SB-505124]] | ||
*[[SCH28080]] | *[[SCH28080]] | ||
*[[SNAP]] | *[[SNAP]] | ||
*[[sodium nitroprusside]] | *[[sodium nitroprusside]] | ||
*[[sodium perchlorate]] | |||
*[[SP600125 ]] | *[[SP600125 ]] | ||
*[[SU5402]] | *[[SU5402]] | ||
| Line 185: | Line 197: | ||
*[[nicardipine]] | *[[nicardipine]] | ||
*[[Nu6102]] | *[[Nu6102]] | ||
*[[purmorphamine]] | *[[purmorphamine]] | ||
*[[Pyrazoleanthrone]] | *[[Pyrazoleanthrone]] | ||
| Line 197: | Line 208: | ||
*[[U0126]] | *[[U0126]] | ||
*[[ursodeoxycholic acid]] | *[[ursodeoxycholic acid]] | ||
*[[valproic acid (VPA)]] | |||
*[[Echinomycin]] | *[[Echinomycin]] | ||
*[[Gö 6983]] | *[[Gö 6983]] | ||
| Line 214: | Line 226: | ||
*[[olomoucine]] | *[[olomoucine]] | ||
*[[RO-3306]] | *[[RO-3306]] | ||
*[[R-roscovitine]] | |||
===ERK/MAPK=== | ===ERK/MAPK=== | ||
| Line 245: | Line 258: | ||
*[[cyclopamine]] | *[[cyclopamine]] | ||
*[[purmorphamine]] | *[[purmorphamine]] | ||
*[[Hh-Ag1.8]] | |||
*[[Vismodegib]] | *[[Vismodegib]] | ||
| Line 252: | Line 266: | ||
===Thyroid Signaling=== | ===Thyroid Signaling=== | ||
*[[ | *[[NH-3]] | ||
===Wnt=== | ===Wnt=== | ||
| Line 300: | Line 314: | ||
*[[cytochalasin D]] | *[[cytochalasin D]] | ||
*[[Colcemide]] | *[[Colcemide]] | ||
*[[Colchicine]] | |||
*[[jasplakinolide]] is an activator | *[[jasplakinolide]] is an activator | ||
*[[latrunculin B]] | *[[latrunculin B]] | ||
| Line 310: | Line 325: | ||
*[[olomoucine]] | *[[olomoucine]] | ||
*[[PD-407824]] | *[[PD-407824]] | ||
===Cell migration, including specific cell lineage removal=== | |||
*[[Clodronate]] | |||
===Cilia=== | ===Cilia=== | ||
*[[methylcellulose (MC)]] | *[[methylcellulose (MC)]] | ||
| Line 319: | Line 337: | ||
===DNA Synthesis=== | ===DNA Synthesis=== | ||
*[[Calyculin A]] | *[[Calyculin A]] | ||
===DNA mutagenic compounds=== | |||
*[[ENU or N-nitroso-N-ethylurea]] 100mM Sigma N3385 | |||
===Growth Cone, Filopodia, and other Cytoskeletal projections=== | ===Growth Cone, Filopodia, and other Cytoskeletal projections=== | ||
| Line 358: | Line 380: | ||
*[[AM281]] | *[[AM281]] | ||
*[[LY320135]] | *[[LY320135]] | ||
*[[bafilomycin A1]] | |||
===G Protein Receptors=== | ===G Protein Receptors=== | ||
*[[purmorphamine]] | *[[purmorphamine]] | ||
| Line 393: | Line 417: | ||
==Models of Anemia== | ==Models of Anemia== | ||
*[[Phenylhydrazine]] | *[[Phenylhydrazine]] | ||
==Environmental toxins== | |||
*[[Cis-bifenthrin (cis-BF)]] | |||
*[[Graphine (GO)]] | |||
*[[4-methylcyclohexane methanol (MCHM)]] | |||
*[[4-octylphenol (OP)]] | |||
*[[metamifop]] | |||
Latest revision as of 07:21, 16 May 2023
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Important small molecule references
- Database of Small Molecules by Feldman and Hogue 2006 at PubChem
- Wnt/Notch by Myers and Krieg 2014
- Ubiquitin-proteasome by Salic and King 2005
Alphabetical List of Small Molecules With Literature References
- 1,3-Dicyclohexylurea
- 11-cis retinal
- 18alpha-glycyrrhetinic acid
- 2'-deoxyadenosine
- 2-APB
- 2-Deoxyglucose
- 3,3,5-triiodothyronine (T3)
- 5HT (seratonin)
- 8-Pcpt-2-O-Me-cAMP-AM
- activin
- Adenosine, periodate oxidized
- AG1296
- AG1879
- AGN193109
- alpha-amanitin
- Alisertib
- anandamide
- AP-III-a4
- apelin
- aphidicolin
- Aroclor 1254
- Atrazine
- AZD1480
- Bafilomycin A1
- BAPTA-AM
- Barasertib
- Benzaldehyde, 3-allyl-2-(2-(diethylamino)ethoxy)-(DEAB)
- beta-xyloside
- blebbistatin
- BMS-453
- Brefeldin A (BFA)
- bumetanide
- calcium ionophore
- canertinib
- CGP54626
- Chelerythrine
- chenodeoxycholic acid
- chlorpromazine
- chymostatin
- Citral
- Colcemide
- concanamycin
- CP-91149
- cycloheximide
- cyclopamine
- Cyclosporin A
- Cytochalasin B
- cytochalasin D
- D-AP5
- D-NAME
- deltamethrin
- dexamethosone
- DHT(dihydrotestosterone)
- diazepam
- Difopein
- Diphenyleneiodonium Chloride
- DMH-1
- Dorsomorphin
- DRB
- Ex-527
- finasteride
- folic acid
- forskolin
- fusicoccin
- gallein
- GANT 61
- gentamycin
- GSK3-inhibitor IX (BIO)
- GM6001
- H-89 Dihydrochloride
- heptanol
- herbimycin A
- Hh-Ag1.8
- Hydroxyurea
- IBMX
- Iodoacetic acid
- jasplakinolide
- 6-B345TTQ
- Ketamine
- KT 5720
- L-NAME
- lansoprazole
- latrunculin A
- latrunculin B
- LDN-193189
- Leflunomide
- leucovorin
- LiCl
- Lovastatin
- LY294002
- m-3M3FBS
- methotrexate (MTX)
- metronidazole
- Mg132
- MK-2206
- MMP-2 inhibitor II
- MS-275
- Mubritinib
- nicorandil
- Nicotinamide
- Nicotinic acid
- nifedipine
- nocodazole
- NSC-87877
- o-phenanthroline
- okadaic acid
- olomoucine
- ouabain
- Olygomycin
- PD173074
- PD-407824
- p-MPPI
- Paclitaxel
- phaclofen
- phenylthiourea (PTU)
- Picropodophyllin
- PMA
- PP2
- primaquine
- Progesterone
- propylthiouracil
- psoralen
- pyrimethamine
- quinpirole
- rac1 inhibitor
- rapamycin
- retinoic acid
- Retinol
- RO-3306
- RS67333
- RU486
- SAHA
- SB 203580
- SB431542
- SB-505124
- SCH28080
- SNAP
- sodium nitroprusside
- sodium perchlorate
- SP600125
- SU5402
- SU6656
- Suramin
- tautomycin
- taxol
- thyroxine (T4)
- Torin 2
- Trichostatin A
- trimetrexate
- Triptolide
- TTNPB
- Tubercidin
- tunicamycin
- Tyrphostin AG 1478
- U73122
- Y27632
- ZM 447439
The Following are in need of standardization and curation
- AM251
- AM281
- AP1510
- AR-A014418
- BHQ
- b-aminoproprionitrile
- beclomethasone
- Butyrate
- calcicludine
- Calyculin A
- celastrol
- celecoxib
- chromanol 293B
- chlorate
- cytochalasin D
- colchicine
- dimethyloxallyl glycine (DMOG)
- diclofenac
- etoposide
- IWR1
- GW843682X
- leptomycin B
- LY320135
- methylcellulose (MC)
- methimazole
- MBCD or MBetaCD
- MS222
- nicardipine
- Nu6102
- purmorphamine
- Pyrazoleanthrone
- R(+)BayK 8644
- RHC80267
- RL-3
- SAG
- SB-431542
- TG003
- Thapsigargin
- U0126
- ursodeoxycholic acid
- valproic acid (VPA)
- Echinomycin
- Gö 6983
- phenylhydrazine
- ω-conotoxin–GVIA
- flunarizine
- tetrodotoxin
- veratridine
- NBI-27914
Small Molecules Affecting Pathways
cAMP
CDK/Cyclins
ERK/MAPK
Folic Acid
JAK/STAT
JNK
Nitric Oxide
PDGF
Retinoic Acid
Shh
TGF-beta/BMP
Thyroid Signaling
Wnt
Epigenetics
Protease Inhibitors
- chymostatin
- GM6001 (MMP inhibitor)
- o-phenanthroline(MMP inhibitor)
- BB-94 MMP inhibitor
- GI254023X MMP10 inhibitor
Small Molecules affecting Biological Functions & Processes
Angiogenesis
Apoptosis
Autophagy
Calcium Signaling
Circadian Rhythm
Cytoskeletal Inhibitors
- Cytochalasin B
- cytochalasin D
- Colcemide
- Colchicine
- jasplakinolide is an activator
- latrunculin B
- taxol
- Paclitaxel
Cell Cycle, including mitosis
Cell migration, including specific cell lineage removal
Cilia
DNA Damage/Repair
DNA Synthesis
DNA mutagenic compounds
- ENU or N-nitroso-N-ethylurea 100mM Sigma N3385
Growth Cone, Filopodia, and other Cytoskeletal projections
- PP2
- SU6656
- cytochalasin D 0.1 uM Sigma
- latrunculin B 30nM Sigma
- colchicine 12.5uM Sigma
- nocodazole 0.1uM Sigma
- RHC80267
Hatching
Left-Right Patterning
Metamorphosis
Neurotransmission
Protein Recycling
Drugs by Gene Class
Channels, including ATPases
G Protein Receptors
Kinases
Phosphatases
Small GTPases
Protein Synthesis
- anisomycin 40uM Sigma
- cycloheximide 40uM
Retinoids
- TTNPB Sigma
Textpresso Small Molecules to Research
- importazole inhibits importin
- M119
- GBG or GBetaGamma or G Protein Beta Gamma
- LY-294002 inhibits PI3K and autophagy