XB-FEAT-5909231: Difference between revisions
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= | =''tmem278''= | ||
This is the community wiki page for the gene '' | This is the community wiki page for the gene ''tmem278'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase. | ||
=nomenclature changes= | |||
23FEB2025 | |||
Following review by HGNC and RefSeq [RSCOM-818], the nomenclature for these genes has changed due to a symbol clash with zebrafish. As Xenopus and other models follow human nomenlcature the following genes will all change from ''tmem88b'' to ''tmem278''. | |||
Issue: Human has TMEM88 (GeneID: 92162) and zebrafish has named the two orthologs as tmem88a (ZDB-GENE-040426-1808, GeneID: 402969) and tmem88b (ZDB-GENE-060929-644, GeneID: 100004517). Unfortunately, human also has TMEM88B (GeneID: 643965) which is orthologous to zebrafish GeneID:101887175 (no official symbol. NCBI calls it tmem88b-like). So, while the zebrafish tmem88a/b genes are orthologs of human TMEM88 there's potential confusion about the orthology to human TMEM88B - particularly since there's no official zebrafish symbol yet for the orthologous GeneID:101887175. | |||
Solution: Human TMEM88B to TMEM278 is an agreeable solution to all concerned parties. These are the TMEM88B orthologs that will have their symbols updated to TMEM278. ZDB-GENE-060929-644, GeneID: 100004517 would remain as tmem88b: | |||
Hs GeneID: 643965 HGNC:37099 | |||
Mm GeneID: 320587 MGI:2444329 | |||
Rn GeneID: 680723 RGD:1588243 | |||
Gg GeneID: 419414 CGNC:50993 | |||
Xtr GeneID: 100380134 | |||
Dr GeneID: 101887175 | |||
Ptr GeneID: 107973858 VGNC:58843 | |||
Bt GeneID: 767837 VGNC:36121 | |||
Ss GeneID: 100526055 VGNC:94215 | |||
Ec GeneID: 100629449 VGNC:111073 | |||
Cf GeneID: 100684204 VGNC:47612 | |||
Fc GeneID: 101085789 VGNC:66369 | |||
Mmul GeneID: 100427005 | |||
Latest revision as of 07:45, 25 February 2025
tmem278
This is the community wiki page for the gene tmem278 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.
nomenclature changes
23FEB2025
Following review by HGNC and RefSeq [RSCOM-818], the nomenclature for these genes has changed due to a symbol clash with zebrafish. As Xenopus and other models follow human nomenlcature the following genes will all change from tmem88b to tmem278.
Issue: Human has TMEM88 (GeneID: 92162) and zebrafish has named the two orthologs as tmem88a (ZDB-GENE-040426-1808, GeneID: 402969) and tmem88b (ZDB-GENE-060929-644, GeneID: 100004517). Unfortunately, human also has TMEM88B (GeneID: 643965) which is orthologous to zebrafish GeneID:101887175 (no official symbol. NCBI calls it tmem88b-like). So, while the zebrafish tmem88a/b genes are orthologs of human TMEM88 there's potential confusion about the orthology to human TMEM88B - particularly since there's no official zebrafish symbol yet for the orthologous GeneID:101887175.
Solution: Human TMEM88B to TMEM278 is an agreeable solution to all concerned parties. These are the TMEM88B orthologs that will have their symbols updated to TMEM278. ZDB-GENE-060929-644, GeneID: 100004517 would remain as tmem88b:
Hs GeneID: 643965 HGNC:37099
Mm GeneID: 320587 MGI:2444329
Rn GeneID: 680723 RGD:1588243
Gg GeneID: 419414 CGNC:50993
Xtr GeneID: 100380134
Dr GeneID: 101887175
Ptr GeneID: 107973858 VGNC:58843
Bt GeneID: 767837 VGNC:36121
Ss GeneID: 100526055 VGNC:94215
Ec GeneID: 100629449 VGNC:111073
Cf GeneID: 100684204 VGNC:47612
Fc GeneID: 101085789 VGNC:66369
Mmul GeneID: 100427005