XB-FEAT-940057: Difference between revisions

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08/102026
08/102026


''Xenopus'' gene symbol and name changed names from ''slc18a2, solute carrier family 18 member A2'', to ''scl18a1.2, solute carrier family 18 member A1 gene 2'', prompted by orthology calls from NCBI and supported DIOPT and synteny analysis.  
''Xenopus tropicalis'' gene symbol and name changed names from ''slc18a2, solute carrier family 18 member A2'', to ''scl18a1.2, solute carrier family 18 member A1 gene 2'', prompted by orthology calls from NCBI and supported DIOPT and synteny analysis.
The X. laevis model on this page was previously called
''LOC108711608, synaptic vesicular amine transporter''.
Synteny shows a series of dulicated slc18a1 gene on X. laevis Chr3L, and although not totally resolved or resolveable, this loci seems to be a paralog of the ''scl18a1.1.L'' gene based on AA alignment and ML/NJ trees.  


Note that ''X.tropicalis'' has 3 copies of 'slc18a1' genes (''scl18a1, scl18a1.2''  and ''slc18a1.3'') on Chr3.  
Note that ''X.tropicalis'' has 8 copies of 'slc18a1' genes (scl18a1 through slc18a1.8) on Chr3.


''X. laevis'' similary has 2 copies, ''slc18a1'' and ''slc18a1.2'' on Chr3L.  
''X. laevis'' similary has 10 copies of ''slc18a1'' on Chr3L, and a further 6 copies (including a pseudogene) on Chr3S. However, not all genes are homeologs- many seems to be paralogs within each subgenome.


Note that true ''slc18a2' genes are found on Chr7/7L/7S in ''Xenopus''.
Note that true 'slc18a2' genes are found on Chr7/7L/7S in ''Xenopus''.

Latest revision as of 13:10, 14 October 2026

slc18a1.2

This is the community wiki page for the gene slc18a1.2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

04/22/ 2016

Human name has changed for Entrez Gene: 6571. From solute carrier family 18 (vesicular monoamine transporter), member 2 to solute carrier family 18 member A2.

08/102026

Xenopus tropicalis gene symbol and name changed names from slc18a2, solute carrier family 18 member A2, to scl18a1.2, solute carrier family 18 member A1 gene 2, prompted by orthology calls from NCBI and supported DIOPT and synteny analysis. The X. laevis model on this page was previously called LOC108711608, synaptic vesicular amine transporter. Synteny shows a series of dulicated slc18a1 gene on X. laevis Chr3L, and although not totally resolved or resolveable, this loci seems to be a paralog of the scl18a1.1.L gene based on AA alignment and ML/NJ trees.

Note that X.tropicalis has 8 copies of 'slc18a1' genes (scl18a1 through slc18a1.8) on Chr3.

X. laevis similary has 10 copies of slc18a1 on Chr3L, and a further 6 copies (including a pseudogene) on Chr3S. However, not all genes are homeologs- many seems to be paralogs within each subgenome.

Note that true 'slc18a2' genes are found on Chr7/7L/7S in Xenopus.