XB-FEAT-995844: Difference between revisions
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=insc= | =insc= | ||
This is the community wiki page for the gene ''insc'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | This is the community wiki page for the gene ''insc'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase. | ||
=nomenclature changes= | |||
05/29/2017 | |||
Human name has changed for Entrez Gene: 387755. From inscuteable homolog (Drosophila) to INSC, spindle orientation adaptor protein. | |||
=summary= | |||
In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically localized multiprotein signaling complexes that are tethered by Inscuteable, which regulates their apical localization (Izaki et al., 2006 [PubMed 16458856]).[supplied by OMIM, Mar 2008] | |||
Latest revision as of 08:12, 31 May 2017
insc
This is the community wiki page for the gene insc please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.
nomenclature changes
05/29/2017
Human name has changed for Entrez Gene: 387755. From inscuteable homolog (Drosophila) to INSC, spindle orientation adaptor protein.
summary
In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically localized multiprotein signaling complexes that are tethered by Inscuteable, which regulates their apical localization (Izaki et al., 2006 [PubMed 16458856]).[supplied by OMIM, Mar 2008]