XB-FEAT-1012023: Difference between revisions
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=lrrc8a= | =lrrc8a= | ||
This is the community wiki page for the gene ''lrrc8a'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | This is the community wiki page for the gene ''lrrc8a'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase. | ||
=nomenclature changes= | |||
08/07/2017 | |||
Human name has changed for Entrez Gene: 56262. From leucine rich repeat containing 8 family member A to leucine rich repeat containing 8 VRAC subunit A | |||
=summary from NCBI= | |||
This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008] | |||
Latest revision as of 07:31, 8 August 2017
lrrc8a
This is the community wiki page for the gene lrrc8a please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.
nomenclature changes
08/07/2017
Human name has changed for Entrez Gene: 56262. From leucine rich repeat containing 8 family member A to leucine rich repeat containing 8 VRAC subunit A
summary from NCBI
This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]