XB-FEAT-5923224: Difference between revisions
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= | =''glull''= | ||
This is the community wiki page for the gene '' | This is the community wiki page for the gene ''glull''. Please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase. | ||
=protein characterization= | |||
According to EggNog protein homology groupings, these ''glull'' proteins are another copy of glutamate-ammonia ligase, and theres no reason to think they are not real 'glul' paralogs, just not the true irtholog of human GLUL. As frog gene names follow human gene names, and in human it seems this gene is represented/matched ( however you want to say it) to a ncRNA, not a protein coding gene, Xenopus 'glull' hasn't been officially named (by anyone except Xenbase) as yet. | |||
=Synteny and nomenclature changes for ''Xenopus glul'' and ''glull'' genes= | |||
15JUN2025 | |||
Note that there are 2 different 'glutamate-ammonia ligase' genes in ''Xenopus''. | |||
XB-GENEPAGE-5923224 ''glull, glutamate-ammonia ligase like'', are found on Chromsome 8 in the following conserved gene pattern. LACK of Synteny with human mouse chick and/or rat necessitate that these gene names/symbols, '''previously annotated as ''glul''''' , be changed to ''like'' status. | |||
Xla.L: ''fcn2> ...nelfb.L> ... LOC108698160> Xelaev18038263m> ... '''glull.L'''> ... arrdc1.L> ... ehmt1.L>'' | |||
Xla.S: ''LOC108699888 [prov:fcn2] LOC108700639 [provl:glul]> ... '''glull.S'''> ...arrdc1.S> ... ehmt1.S>'' | |||
X.trop: ''fcn2l > ... nelfb > ... LOC116406908< ... LOC100498257/gllull [glutamine synthetase] > ... '''glul'''> ... arrdc1> ... ehmt1''> | |||
XB-GENEPAGE-990052 TRUE GLUL orthologs , named ''glul, glutamate-ammonia ligase'' are found on Chromosome 4. This is supported by synteny. These ''glul'' genes previously had the ''like'' status. | |||
Xla.L: d''hx9.L< .. npl.L< ... rgs8.L> ... rgs16.L> ... '''glul.L''' > LOC108713540 [provisional:zfp989.L]> ... cacna1e.L<'' | |||
Xla.S: ''dhx9.S< .. npl.S< ... rgs8.S> ... rgs16.S> ... '''glul.S'''> Xelaev18025342m.S> ... LOC108715639/cacna1e.S<'' | |||
Xtrop: ''dhx9< .. npl< ... rgs8> ... rgs16> ... '''LOC394904/glul''' > znf91> ... cacna1e<'' | |||
Latest revision as of 18:46, 15 June 2026
glull
This is the community wiki page for the gene glull. Please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.
protein characterization
According to EggNog protein homology groupings, these glull proteins are another copy of glutamate-ammonia ligase, and theres no reason to think they are not real 'glul' paralogs, just not the true irtholog of human GLUL. As frog gene names follow human gene names, and in human it seems this gene is represented/matched ( however you want to say it) to a ncRNA, not a protein coding gene, Xenopus 'glull' hasn't been officially named (by anyone except Xenbase) as yet.
Synteny and nomenclature changes for Xenopus glul and glull genes
15JUN2025
Note that there are 2 different 'glutamate-ammonia ligase' genes in Xenopus.
XB-GENEPAGE-5923224 glull, glutamate-ammonia ligase like, are found on Chromsome 8 in the following conserved gene pattern. LACK of Synteny with human mouse chick and/or rat necessitate that these gene names/symbols, previously annotated as glul , be changed to like status.
Xla.L: fcn2> ...nelfb.L> ... LOC108698160> Xelaev18038263m> ... glull.L> ... arrdc1.L> ... ehmt1.L>
Xla.S: LOC108699888 [prov:fcn2] LOC108700639 [provl:glul]> ... glull.S> ...arrdc1.S> ... ehmt1.S>
X.trop: fcn2l > ... nelfb > ... LOC116406908< ... LOC100498257/gllull [glutamine synthetase] > ... glul> ... arrdc1> ... ehmt1>
XB-GENEPAGE-990052 TRUE GLUL orthologs , named glul, glutamate-ammonia ligase are found on Chromosome 4. This is supported by synteny. These glul genes previously had the like status.
Xla.L: dhx9.L< .. npl.L< ... rgs8.L> ... rgs16.L> ... glul.L > LOC108713540 [provisional:zfp989.L]> ... cacna1e.L<
Xla.S: dhx9.S< .. npl.S< ... rgs8.S> ... rgs16.S> ... glul.S> Xelaev18025342m.S> ... LOC108715639/cacna1e.S<
Xtrop: dhx9< .. npl< ... rgs8> ... rgs16> ... LOC394904/glul > znf91> ... cacna1e<