XB-FEAT-978289: Difference between revisions
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This is the community wiki page for the gene '' | This is the community wiki page for the gene ''pals1'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | ||
=summary for human PALS1 from NCBI= | |||
This gene encodes a member of the p55-like subfamily of the membrane-associated guanylate kinase (MAGUK) gene superfamily. The encoded protein participates in the polarization of differentiating cells, has been shown to regulate myelinating Schwann cells (PMID: 20237282), and is one of the components of the Crumbs complex in the retina. Mice which express lower levels of the orthologous protein have retinal degeneration and impaired vision (PMID: 22114289). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012] | |||
=nomenclature changes= | |||
03.17.2021 | |||
Human symbol has changed for genepage ID: 978289 From MPP5 to PALS1 | |||
Xenopus symbol has changed for genepage ID: 978289 From mpp5 to pals1 | |||
Human symbol has changed for Entrez Gene: 64398. From MPP5 to PALS1 | |||
Human name has changed for Entrez Gene: 64398. From membrane palmitoylated protein 5 to protein associated with LIN7 1, MAGUK family member | |||
10.20.2021 | |||
Human name has changed for Entrez Gene: 64398 ( PALS1). From protein associated with LIN7 1, MAGUK family member to protein associated with LIN7 1, MAGUK p55 family member | |||
Latest revision as of 12:04, 19 October 2021
pals1
This is the community wiki page for the gene pals1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
summary for human PALS1 from NCBI
This gene encodes a member of the p55-like subfamily of the membrane-associated guanylate kinase (MAGUK) gene superfamily. The encoded protein participates in the polarization of differentiating cells, has been shown to regulate myelinating Schwann cells (PMID: 20237282), and is one of the components of the Crumbs complex in the retina. Mice which express lower levels of the orthologous protein have retinal degeneration and impaired vision (PMID: 22114289). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
nomenclature changes
03.17.2021
Human symbol has changed for genepage ID: 978289 From MPP5 to PALS1
Xenopus symbol has changed for genepage ID: 978289 From mpp5 to pals1
Human symbol has changed for Entrez Gene: 64398. From MPP5 to PALS1
Human name has changed for Entrez Gene: 64398. From membrane palmitoylated protein 5 to protein associated with LIN7 1, MAGUK family member
10.20.2021 Human name has changed for Entrez Gene: 64398 ( PALS1). From protein associated with LIN7 1, MAGUK family member to protein associated with LIN7 1, MAGUK p55 family member