XB-FEAT-5961451: Difference between revisions
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=c6 | =''c6''= | ||
This is the community wiki page for the gene ''c6'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | This is the community wiki page for the gene ''c6'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | ||
=nomenclature changes= | =nomenclature changes= | ||
02.25.20 | 02.25.20 | ||
name changed from 'complement component 6, gene 1' to 'complement C6, gene 1' to follow human nomenclature conventions. | name changed from 'complement component 6, gene 1' to 'complement C6, gene 1' to follow human nomenclature conventions. | ||
Note that Xenopus laevis has a gene duplication of c6 genes, and both are side-by-side on Chr1, and both are orthologous to human C6. | Note that ''Xenopus laevis'' has a gene duplication of c6 genes, and both are side-by-side on Chr1, and both are orthologous to human C6. | ||
''complement C6, gene 1 '' , has symbol ''c6'' and synonym ''c6.1''; the duplicated gene ''complement C6, gene 2'' has symbol ''c6.2'' | |||
=Summary for human C6 from NCBI= | =Summary for human C6 from NCBI= | ||
This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012] | This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012] | ||
Latest revision as of 11:06, 23 September 2024
c6
This is the community wiki page for the gene c6 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
nomenclature changes
02.25.20 name changed from 'complement component 6, gene 1' to 'complement C6, gene 1' to follow human nomenclature conventions.
Note that Xenopus laevis has a gene duplication of c6 genes, and both are side-by-side on Chr1, and both are orthologous to human C6. complement C6, gene 1 , has symbol c6 and synonym c6.1; the duplicated gene complement C6, gene 2 has symbol c6.2
Summary for human C6 from NCBI
This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012]