XB-FEAT-483163: Difference between revisions
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=runx1= | =runx1= | ||
This is the community wiki page for the gene ''runx1'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | This is the community wiki page for the gene ''runx1'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | ||
=nomenclature changes= | |||
04/22/ 2016 | |||
Human name has changed for Entrez Gene: 861. From runt-related transcription factor 1 to runt related transcription factor 1 | |||
05/13/19 | |||
Human name has changed for Entrez Gene: 861. From runt related transcription factor 1 to RUNX family transcription factor 1 | |||
=summary from NCBI= | |||
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | |||
Latest revision as of 11:27, 13 May 2019
runx1
This is the community wiki page for the gene runx1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
nomenclature changes
04/22/ 2016
Human name has changed for Entrez Gene: 861. From runt-related transcription factor 1 to runt related transcription factor 1
05/13/19
Human name has changed for Entrez Gene: 861. From runt related transcription factor 1 to RUNX family transcription factor 1
summary from NCBI
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]