5HT (seratonin): Difference between revisions

Latest revision as of 12:25, 26 June 2017

Description

"Serotonin is a biochemical messenger and regulator, synthesized from the essential amino acid L-Tryptophan. Serotonin in the nervous system acts as a local transmitter at synapses, and as a paracrine or hormonal modulator of circuits upon diffusion, allowing a wide variety of "state-dependent" behavioral responses to different stimuli. Serotonin is widely distributed in the nervous system of vertebrates and invertebrates and some of its behavioral effects have been preserved along evolution. Such is the case of aggressive behavior and rhythmic motor patterns, including those responsible for feeding." Extract from Human Metabolome Database.

Seratonin structure, Photo from Sigma-Aldrich

- Genes Affected
- htr1a

Synonyms

Serotonin; 5-HYDROXYTRYPTAMINE; 3-(2-Aminoethyl)-1H-indol-5-ol; Enteramine; 50-67-9

Suppliers

Sigma H9523

Usage Notes

1uM

References

>593 references found in Xenopus literature using textpresso

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 ==Description==
-Serotonin is a biochemical messenger and regulator, synthesized from the essential amino acid L-Tryptophan. Serotonin in the nervous system acts as a local transmitter at synapses, and as a paracrine or hormonal modulator of circuits upon diffusion, allowing a wide variety of "state-dependent" behavioral responses to different stimuli. Serotonin is widely distributed in the nervous system of vertebrates and invertebrates and some of its behavioral effects have been preserved along evolution. Such is the case of aggressive behavior and rhythmic motor patterns , including those responsible for feeding.
+"Serotonin is a biochemical messenger and regulator, synthesized from the essential amino acid L-Tryptophan. Serotonin in the nervous system acts as a local transmitter at synapses, and as a paracrine or hormonal modulator of circuits upon diffusion, allowing a wide variety of "state-dependent" behavioral responses to different stimuli. Serotonin is widely distributed in the nervous system of vertebrates and invertebrates and some of its behavioral effects have been preserved along evolution. Such is the case of aggressive behavior and rhythmic motor patterns, including those responsible for feeding." Extract from [http://www.hmdb.ca/metabolites/HMDB00259 Human Metabolome Database].
 [[File:SeratoninSigma.png|frame|right|Seratonin structure, Photo from Sigma-Aldrich]]
 **Genes Affected
 **[http://www.xenbase.org/gene/showgene.do?method=display&geneId=984749 htr1a]
 ==Synonyms==
 Serotonin; 5-HYDROXYTRYPTAMINE; 3-(2-Aminoethyl)-1H-indol-5-ol; Enteramine; 50-67-9
@@ Line 17: / Line 19: @@
 *[https://pubchem.ncbi.nlm.nih.gov/compound/5202 PubChem]
 *[http://www.xenbase.org/literature/article.do?method=display&articleId=11986 Kim et al., 1999]
-Search for more references using [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
+*[http://ctdbase.org/detail.go?type=chem&acc=D012701 Comparative Toxicogenomics Database]
-*
+>593 references found in Xenopus literature using [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search?searchstring=5-HydroxyTryptamine;exactmatch=on;searchsynonyms=on;cat1=Select%20category%201%20from%20list%20above;cat2=Select%20category%202%20from%20list%20above;cat3=Select%20category%203%20from%20list%20above;cat4=Select%20category%204%20from%20list%20above;cat5=Select%20category%205%20from%20list%20above;literature=xenopus;target=abstract;target=materials;target=acknowledgments;target=non-sectioned;target=references;target=conclusion;target=results;target=discussion;target=title;target=introduction;sentencerange=sentence;sort=score%20%28hits%29;supplementals=on;mode=boolean;authorfilter=;journalfilter=;yearfilter=;docidfilter=;search=Search%21;disp_author=on;disp_accession=on;disp_bib=on;disp_type=on;disp_abstract=on;disp_title=on;disp_citation=on;disp_journal=on;disp_year=on;disp_supplementals=on;disp_epp=2000;disp_matches=subscore-sorted;disp_textlinks=on;disp_searchterm-highlighting=off;;disp_search-options=on;checksearchfilename=%2Ftmp%2Ftextpresso%2F%2Ftmp%2FfileWWe8ZK;searchfilename=%2Ftmp%2Ftextpresso%2F%2Ftmp%2FfilerA7WuW;tqueryfilename=%2Ftmp%2Ftextpresso%2F%2Ftmp%2FfileEck4Z7;filteredfilename=%2Ftmp%2Ftextpresso%2F%2Ftmp%2Ffilevdoqvj;page=1;.cgifields=casesensitive;.cgifields=searchsynonyms;.cgifields=target;.cgifields=fuabstracts;.cgifields=supplementals;.cgifields=mtabstracts;.cgifields=exactmatch;disp_expand-sentences=off textpresso]
 *[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]