Cytochalasin B: Difference between revisions
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Cell permeable fungal toxin that disrupts contractile microfilaments by inhibiting actin polymerization. This, in turn, induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport." | Cell permeable fungal toxin that disrupts contractile microfilaments by inhibiting actin polymerization. This, in turn, induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport." | ||
**-Sigma Description | **-Sigma Description | ||
==Genes Affected== | |||
**[http://www.xenbase.org/gene/showgene.do?method=display&geneId=490882& actb] | **[http://www.xenbase.org/gene/showgene.do?method=display&geneId=490882& actb] | ||
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==References== | ==References== | ||
*[https://pubchem.ncbi.nlm.nih.gov/compound/5311281 PubChem] | |||
*[http://www.xenbase.org/literature/article.do?method=display&articleId=26343 Jones et al., 1989] | *[http://www.xenbase.org/literature/article.do?method=display&articleId=26343 Jones et al., 1989] | ||
*[http://www.xenbase.org/literature/article.do?method=display&articleId=27040 Yisraeli et al., 1989] | *[http://www.xenbase.org/literature/article.do?method=display&articleId=27040 Yisraeli et al., 1989] | ||
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>640 Xenbase articles contain a reference to Cytochalasin B according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso] | >640 Xenbase articles contain a reference to Cytochalasin B according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso] | ||
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]] | |||
Latest revision as of 12:41, 2 June 2015
Description
Inhibits cytoskeletal assembly and thereby gastrulation.
"One of a group of fungal metabolites that interfere with a wide variety of cellular movements. Useful tool for characterizing some of the polymerization properties of actin,1 and in studies on cytokinesis.2 Probe for the two hexose-transport systems in rat L6 myoblasts.3 Cell permeable fungal toxin that disrupts contractile microfilaments by inhibiting actin polymerization. This, in turn, induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport."
- -Sigma Description
Genes Affected
Suppliers
Usage Notes
10ug/mL in MBS
References
>640 Xenbase articles contain a reference to Cytochalasin B according to textpresso