Tunicamycin: Difference between revisions
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imported>Kevin Created page with "==Description== [[File:______|frame|right|_______ structure, photo from Sigma-Aldrich]] ==Genes Affected== ==Suppliers== *[http://www.xenbase.org/entry/ SORRYONLYALINKTOXENB..." |
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==Description== | ==Description== | ||
[[File: | "Application: Tunicamycin has been used to study the effect of N-linked glycosylation of human proton-coupled folate transporter (HsPCFT) in HeLa cells1. Tunicamycin has also been used to study the functional effects of coxsackievirus and adenovirus receptor (CAR) glycosylation in COS-7 cells2. | ||
Biochem/physiol Actions: Antibacterial and antifungal. Blocks the formation of protein N-glycosidic linkages by inhibiting the transfer of N-acetylglucosamine 1-phosphate to dolichol monophosphate. Inhibits bacterial and eukaryote N-acetylglucosamine transferases and prevents formation of N-acetylglucosamine lipid intermediates." | |||
*-Sigma Product Description | |||
[[File:tunicamycin.png|frame|right|tunicamycin structure, photo from Sigma-Aldrich]] | |||
==Genes Affected== | ==Genes Affected== | ||
==Suppliers== | ==Suppliers== | ||
*[http://www. | *[http://www.sigmaaldrich.com/catalog/product/sigma/t7765?lang=en®ion=US Sigma T7765] | ||
==Usage Notes== | ==Usage Notes== | ||
1mg/mL in DMSO diluted 1:10 in water | |||
==References== | ==References== | ||
*[https://pubchem.ncbi.nlm.nih.gov/ Pubchem] | *[https://pubchem.ncbi.nlm.nih.gov/ Pubchem] | ||
*[http://www.xenbase.org/literature/article.do?method=display&articleId= | *[http://www.xenbase.org/literature/article.do?method=display&articleId=49898 Marti et al., 2013] | ||
> | > 393 Xenbase articles contain a reference to tunicamycin according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso] | ||
* | * | ||
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]] | *[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]] | ||
Latest revision as of 13:26, 2 July 2015
Description
"Application: Tunicamycin has been used to study the effect of N-linked glycosylation of human proton-coupled folate transporter (HsPCFT) in HeLa cells1. Tunicamycin has also been used to study the functional effects of coxsackievirus and adenovirus receptor (CAR) glycosylation in COS-7 cells2. Biochem/physiol Actions: Antibacterial and antifungal. Blocks the formation of protein N-glycosidic linkages by inhibiting the transfer of N-acetylglucosamine 1-phosphate to dolichol monophosphate. Inhibits bacterial and eukaryote N-acetylglucosamine transferases and prevents formation of N-acetylglucosamine lipid intermediates."
- -Sigma Product Description
Genes Affected
Suppliers
Usage Notes
1mg/mL in DMSO diluted 1:10 in water
References
> 393 Xenbase articles contain a reference to tunicamycin according to textpresso