XB-FEAT-22172581: Difference between revisions
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=dtx3-like= | =''dtx3-like''= | ||
This is the community wiki page for the gene ''dtx3-like'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | This is the community wiki page for the gene ''dtx3-like'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase. | ||
=nomenclature changes= | =nomenclature changes= | ||
1.3.2020 | 1.3.2020 | ||
6.30.20: Following Entrz report: | gene page created for dtx3-like | ||
6.30.20: | |||
Following Entrz report: | |||
Human symbol has changed for genepage ID: 22172581 From dtx3-like to DTX3 | Human symbol has changed for genepage ID: 22172581 From dtx3-like to DTX3 | ||
| Line 12: | Line 16: | ||
Human name has changed for genepage ID: 22172581 From deltex 3, E3 ubiquitin ligase-like to deltex E3 ubiquitin ligase 3 | Human name has changed for genepage ID: 22172581 From deltex 3, E3 ubiquitin ligase-like to deltex E3 ubiquitin ligase 3 | ||
8.19.2020: This gene is in fact the dtx3-''like'' gene ''dtex3-like, deltex E3 ubiquitin ligase 3-like'' on Chromsome 8 in ''Xenopus''. | 8.19.2020: | ||
This gene is in fact the dtx3-''like'' gene ''dtex3-like, deltex E3 ubiquitin ligase 3-like'' on Chromsome 8/8L in ''Xenopus''. We have given it an extra serial number (2) to distinguish from the other ''dtx3l deltex E3 ubiquitin ligase 3L'' on Scaffold734/9_10L/S, which is the true ortholog of the Human DTX3L. | |||
Note that in ''X. laevis'' v9.2 genome annotation, this region of the Chromosome 8 is poorly annotated, with most gene models uncharacterized and unnamed, so synteny is difficult to establish with certainty, and it differs considerably from the ''X. tropicalis'' v10.0 annotation. | |||
In | In ''X. tropicalis'' genome '''v9.1''' this gene is found in this gene order: cd163> cd5l> cd163 '''dtx3-like'''< LOC#(vm2r26)< LOC#(gprc6a)< | ||
In X. tropicalis v10.0 genome annotation , it is called LOC550107 and | In ''X. tropicalis'' '''v10.0''' genome annotation, it is called LOC550107 and dtx3-like.1 in the lift over file. These are added as synonyms to this genepage. | ||
We have removed ortholog links as these are yet to be confirmed. | We have removed ortholog links as these are yet to be confirmed. | ||
WARNING: there are 2 other ''deltex 3'' genes in human and Xenopus- ''dtx3'', and ''dtx3L''. | WARNING: NB there are 2 other ''deltex 3'' genes in human and ''Xenopus''- ''dtx3'', and ''dtx3L''. | ||
1) The true ortholog of human DTX3 is ''Xenopus'' ''dtx3'' Gene ID: 2217250, on Chromosome 2, based on conserved gene order/synteny | 1) The true ortholog of human DTX3 is ''Xenopus'' ''dtx3'' Gene ID: 2217250, on Chromosome 2, based on conserved gene order/synteny | ||
2) The true ortholog of human DTX3L is ''Xenopus'' ''dtx3l'' Gene ID:100496352, based on conserved gene order/synteny, which is annotated on Scaffold_734 in | 2) The true ortholog of human DTX3L is ''Xenopus'' ''dtx3l'' Gene ID:100496352, based on conserved gene order/synteny, which is annotated on Scaffold_734 in ''X. tropicalis'' '''v9.1''' (gene model '''gene26586''') and in ''X. laevis'' '''v9.2''' is on Chr9_10 (dtx3l.L gene ID:108701239; dtx3l.S gene ID:108702882). A new genepage is being built on Xenbase for these genes, and the vertebrate orthologs will be moved to this new gene pages. | ||
Note also that the 'L' human in the gene DTX3L, doesn't appear stand for 'like' as it would in a ''Xenopus'' gene name. | |||
19AUG2024 | |||
GENE NAME UPDATE TO deltex E3 ubiquitin ligase 3 like, AND GENE SYMBOL TO dtx3-like on recommendation of TKwon. | |||
Latest revision as of 14:50, 18 August 2024
dtx3-like
This is the community wiki page for the gene dtx3-like please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.
nomenclature changes
1.3.2020
gene page created for dtx3-like
6.30.20:
Following Entrz report:
Human symbol has changed for genepage ID: 22172581 From dtx3-like to DTX3
Human name has changed for genepage ID: 22172581 From deltex 3, E3 ubiquitin ligase-like to deltex E3 ubiquitin ligase 3
8.19.2020:
This gene is in fact the dtx3-like gene dtex3-like, deltex E3 ubiquitin ligase 3-like on Chromsome 8/8L in Xenopus. We have given it an extra serial number (2) to distinguish from the other dtx3l deltex E3 ubiquitin ligase 3L on Scaffold734/9_10L/S, which is the true ortholog of the Human DTX3L.
Note that in X. laevis v9.2 genome annotation, this region of the Chromosome 8 is poorly annotated, with most gene models uncharacterized and unnamed, so synteny is difficult to establish with certainty, and it differs considerably from the X. tropicalis v10.0 annotation.
In X. tropicalis genome v9.1 this gene is found in this gene order: cd163> cd5l> cd163 dtx3-like< LOC#(vm2r26)< LOC#(gprc6a)<
In X. tropicalis v10.0 genome annotation, it is called LOC550107 and dtx3-like.1 in the lift over file. These are added as synonyms to this genepage.
We have removed ortholog links as these are yet to be confirmed.
WARNING: NB there are 2 other deltex 3 genes in human and Xenopus- dtx3, and dtx3L.
1) The true ortholog of human DTX3 is Xenopus dtx3 Gene ID: 2217250, on Chromosome 2, based on conserved gene order/synteny
2) The true ortholog of human DTX3L is Xenopus dtx3l Gene ID:100496352, based on conserved gene order/synteny, which is annotated on Scaffold_734 in X. tropicalis v9.1 (gene model gene26586) and in X. laevis v9.2 is on Chr9_10 (dtx3l.L gene ID:108701239; dtx3l.S gene ID:108702882). A new genepage is being built on Xenbase for these genes, and the vertebrate orthologs will be moved to this new gene pages.
Note also that the 'L' human in the gene DTX3L, doesn't appear stand for 'like' as it would in a Xenopus gene name.
19AUG2024
GENE NAME UPDATE TO deltex E3 ubiquitin ligase 3 like, AND GENE SYMBOL TO dtx3-like on recommendation of TKwon.