XB-FEAT-877260: Difference between revisions
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Based on pattern of synteny, the rergl2 X. tropicalis gene (GeneID:100145332) is | Based on pattern of synteny, the ''rergl2 X. tropicalis'' gene (GeneID:100145332) is '''NOT''' the true ortholog of human RERG nor RERGL. It seems to be a ''Xenopus'' and possibly other amphibian species' gene is very similar to RERGL, so is named is provisionally here with the '2' suffix, assuming it is a unique ''rergl'' gene, but '''not''' a ''.2'' as this is solely used for tandem duplications. | ||
Latest revision as of 08:30, 22 May 2023
rergl2
This is the community wiki page for the gene rergl2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
nomenclature changes
25APRIL2023 Xenopus gene name changed from rergl.2 (provisional) to rergl2 (provisional).
22MAY2023
REMOVED PROVISONAL DB TAGS AND SUFFIXES FROM GENE NAME AND SYMBOL.
synteny and orthology
25April2023
There are 3 'RERG' family genes annotated inv10 genome for Xenopus tropicalis:
1) rerg RAS like estrogen regulated growth inhibitor on chr3/3L. XB-GENEPAGE-489596
2) rergl RERG/RAS-like on Chr3/3L/3S XB-GENEPAGE-6037389
3) rergl2 RAS like estrogen regulated growth inhibitor like 2 (provisional) on Chr4/4L [XB-GENEPAGE-877260] where its is flanked by mrpl21, ighmbp2, syt12 ptdss2 downstream (the upstream the genes are uncharacterized)
Based on pattern of synteny, the rergl2 X. tropicalis gene (GeneID:100145332) is NOT the true ortholog of human RERG nor RERGL. It seems to be a Xenopus and possibly other amphibian species' gene is very similar to RERGL, so is named is provisionally here with the '2' suffix, assuming it is a unique rergl gene, but not a .2 as this is solely used for tandem duplications.