XB-FEAT-22063310: Difference between revisions

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''Xenopus'' gene symbol changed from ''spaca5'' to ''spaca5.2''. Synteny support the other ''spaca5'' gene on chr 8 as the true ortholog of the human SPACA5 gene.
''Xenopus'' gene symbol changed from ''spaca5'' to ''spaca5.2''. Synteny support the other ''spaca5'' gene on chr 8 as the true ortholog of the human SPACA5 gene.


=orthology=
10MARCH2025
26April2023


DIOPT/EggNog analysis of the ''Xenopus'' protein for this gene confirms it as a member of the SPACA5 homology group, and the gene name was updated as indicated.
There were 4 genes annotated as 'spaca5' and 'spaca5l' in the v10 ''Xenopus'' genome assemblies.  


Note that the NCBI/UniProt name for protein needs reassessing ( not dentin sialophosphoprotein-like)
Synteny supports the 2 gene models on Chr8/8L/8S,  as the true orthologs of the human SPACA5 gene.


=protein used in DIOPT analysis=
The names of the ''spaca5'' genes on chr10/9_10L have been changed to 'spaca5-like' genes 1 and 2.
dentin sialophosphoprotein-like [Xenopus tropicalis]


NCBI Reference Sequence: XP_031746799.1
=orthology=
26April2023


>XP_031746799.1 dentin sialophosphoprotein-like [Xenopus tropicalis]
DIOPT/EggNog analysis of the ''Xenopus'' protein for this gene confirms it as a member of the SPACA5 homology group, and the gene name was updated as indicated.
MKLILGLLVLFPWTLRAQDNQMVTSNDSDITTGVNSEQQTDASNSTSDQGSYNNTYNTLTTGSDSYTTET
AAADAPTDSSDPLPTNSSSYNTDGNMLENKDALLVTSVNNNVLESTVMSSSPTSTDSGTYSTAESTVYSL
SKSEGDSASEDQSNENSNSMESEQGDTSCAVYEILREAGMVGYRGLSAADWICVLKMTNLFHPSEKNAVR
CRNLKSHKAKYSCECFGDNVHKYIQCQMKTMRDPTDLWNQFCNGKDLSQYTRACESQLPQEPRKY
 
 
this makes no sense to me - CJZ

Latest revision as of 10:23, 10 March 2025

nomenclature changes

26April2023

Xenopus gene name changed from XB22063310 [provisional] Xenopus laevis cell surface glycoprotein 1-like, to spaca5, sperm acrosome associated 5

08MARCH20205

Xenopus gene symbol changed from spaca5 to spaca5.2. Synteny support the other spaca5 gene on chr 8 as the true ortholog of the human SPACA5 gene.

10MARCH2025

There were 4 genes annotated as 'spaca5' and 'spaca5l' in the v10 Xenopus genome assemblies.

Synteny supports the 2 gene models on Chr8/8L/8S, as the true orthologs of the human SPACA5 gene.

The names of the spaca5 genes on chr10/9_10L have been changed to 'spaca5-like' genes 1 and 2.

orthology

26April2023

DIOPT/EggNog analysis of the Xenopus protein for this gene confirms it as a member of the SPACA5 homology group, and the gene name was updated as indicated.