XB-FEAT-5749040: Difference between revisions
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='' | =''rbp''= | ||
This is the community wiki page for the gene '' | This is the community wiki page for the gene ''rbp'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase. | ||
=summary for human IZUMO1R from alliance and NCBI= | =summary for human IZUMO1R from alliance and NCBI= | ||
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As NCBI do not list the ''Xenopus'' ''izumo1r'' genes as orthologs of the same named human, mouse or rat genes, these orthologs have been removed from the ''Xenopus'' gene page. | As NCBI do not list the ''Xenopus'' ''izumo1r'' genes as orthologs of the same named human, mouse or rat genes, these orthologs have been removed from the ''Xenopus'' gene page. | ||
Note that phylogenetic analysis by Fukimoto et al (2025) also demostartes that ''X. laevis folr4.L'' and ''X. tropicalis folr4'' are not orthologous to mammalian Folr4/IZUMO1R, but rather encode a Rfbp protein. | Note that phylogenetic analysis by Fukimoto et al (2025) also demostartes that ''X. laevis folr4.L'' and ''X. tropicalis folr4'' are not orthologous to mammalian Folr4/IZUMO1R, but rather encode a Rfbp protein (the chicken accession NM_205463 in the phlygram /tree below labelled RFBP = Gallus Gene ID: 396449, RBP riboflavin binding protein. ) | ||
[[File:1-s2.0-S0012160625003136-gr6 lrg.jpg|thumb]] | [[File:1-s2.0-S0012160625003136-gr6 lrg.jpg|thumb]] | ||
Latest revision as of 19:50, 20 May 2026
rbp
This is the community wiki page for the gene rbp please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.
summary for human IZUMO1R from alliance and NCBI
Enables signaling receptor activity. Involved in fusion of sperm to egg plasma membrane involved in single fertilization. Located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
orthology notes
As NCBI do not list the Xenopus izumo1r genes as orthologs of the same named human, mouse or rat genes, these orthologs have been removed from the Xenopus gene page.
Note that phylogenetic analysis by Fukimoto et al (2025) also demostartes that X. laevis folr4.L and X. tropicalis folr4 are not orthologous to mammalian Folr4/IZUMO1R, but rather encode a Rfbp protein (the chicken accession NM_205463 in the phlygram /tree below labelled RFBP = Gallus Gene ID: 396449, RBP riboflavin binding protein. )
