XB-FEAT-486324: Difference between revisions
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= | =cltrn= | ||
This is the community wiki page for the gene '' | This is the community wiki page for the gene ''cltrn'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | ||
For a laevis probe use OpenBiosystems CloneID 4031619 | For a laevis probe use OpenBiosystems CloneID 4031619 | ||
=NCBI Summary= | |||
This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells. [provided by RefSeq, Jun 2013]. | |||
=nomenclature changes= | |||
12/18/2017 | |||
Human symbol has changed for genepage ID: 486324 From tmem27 to cltrn | |||
Human symbol has changed for Entrez Gene: 57393. From TMEM27 to CLTRN | |||
Human name has changed for Entrez Gene: 57393. From transmembrane protein 27 to collectrin, amino acid transport regulator | |||
Latest revision as of 07:32, 3 January 2018
cltrn
This is the community wiki page for the gene cltrn please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
For a laevis probe use OpenBiosystems CloneID 4031619
NCBI Summary
This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells. [provided by RefSeq, Jun 2013].
nomenclature changes
12/18/2017 Human symbol has changed for genepage ID: 486324 From tmem27 to cltrn
Human symbol has changed for Entrez Gene: 57393. From TMEM27 to CLTRN
Human name has changed for Entrez Gene: 57393. From transmembrane protein 27 to collectrin, amino acid transport regulator