XB-FEAT-962426: Difference between revisions

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=top1mt=  
=top1mt=  
This is the community wiki page for the gene ''top1mt'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
This is the community wiki page for the gene ''top1mt'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
=nomenclature changes=
08/07/2017
Human name has changed for Entrez Gene: 116447. From topoisomerase (DNA) I, mitochondrial to DNA topoisomerase I mitochondrial
=summary from NCBI=
This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]

Latest revision as of 07:39, 8 August 2017

top1mt

This is the community wiki page for the gene top1mt please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

08/07/2017

Human name has changed for Entrez Gene: 116447. From topoisomerase (DNA) I, mitochondrial to DNA topoisomerase I mitochondrial

summary from NCBI

This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]