Concanamycin: Difference between revisions
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==References== | ==References== | ||
*[https://pubchem.ncbi.nlm.nih.gov/compound/23724569 PubChem] | |||
*[http://www.xenbase.org/literature/article.do?method=display&articleId=6115 Cheng et al., 2002] | *[http://www.xenbase.org/literature/article.do?method=display&articleId=6115 Cheng et al., 2002] | ||
Latest revision as of 12:38, 2 June 2015
Description
V-ATPase inhibitor, see fusicoccin for an activator.
"Cytotoxic. Inhibits acidification of organelles and perforin-mediated cytotoxicity."
- -Sigma Description
"Specific inhibitor of V-type (vacuolar) H+-ATPase that displays > 2000-fold selectivity over other H+-ATPases (IC50 values are 9.2, > 20000, > 20000 and > 20000 nM for yeast V-type, F-type, P-type H+-ATPases and porcine P-type Na+,K+-ATPase respectively). Blocks cell surface expression of virus envelope glycoproteins without affecting synthesis and exhibits cytotoxicity in several cell lines."
- -Tocris Description
Suppliers
Usage Notes
2M
References
>11 Xenbase articles contain a reference to concanamycin according to textpresso including these: