RU486: Difference between revisions

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imported>Kevin
Created page with "==Description== [[File:______|frame|right|_______ structure, photo from Sigma-Aldrich]] ==Genes Affected== ==Suppliers== *[http://www.xenbase.org/entry/ SORRYONLYALINKTOXENB..."
 
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==Description==
==Description==
[[File:______|frame|right|_______ structure, photo from Sigma-Aldrich]]
Synonym: Mifepristone
"Mifepristone is a progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary CUSHING SYNDROME."
*-Pubchem Description
 
[[File:RU486.png|frame|right|RU486 structure, photo from pubchem]]


==Genes Affected==
==Genes Affected==
*[http://www.xenbase.org/gene/showgene.do?method=display&geneId=945014 creb1]


==Suppliers==
==Suppliers==
*[http://www.xenbase.org/entry/ SORRYONLYALINKTOXENBASE]
*[http://www.sigmaaldrich.com/catalog/product/sigma/m8046?lang=en&region=US Sigma]


==Usage Notes==
==Usage Notes==


==References==
==References==
*[https://pubchem.ncbi.nlm.nih.gov/ Pubchem]
*[https://pubchem.ncbi.nlm.nih.gov/compound/55245 Pubchem]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=__________ ____ et al., 2xxxx]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=12136 Lutz et al., 1999]


>___ Xenbase articles contain a reference to _____ according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
>43 Xenbase articles contain a reference to RU486 according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
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*
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]

Revision as of 10:39, 26 June 2015

Description

Synonym: Mifepristone "Mifepristone is a progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary CUSHING SYNDROME."

  • -Pubchem Description
RU486 structure, photo from pubchem

Genes Affected

Suppliers

Usage Notes

References

>43 Xenbase articles contain a reference to RU486 according to textpresso