Barasertib: Difference between revisions

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Created page with "==Description== Barasertib specifically binds to and inhibits Aurora kinase B, which results in the disruption of spindle checkpoint functions and chromosome alignment and, so..."
 
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==References==
==References==
*[https://pubchem.ncbi.nlm.nih.gov/compound/11497983 NCBI PubChem CID:11497983
*[https://pubchem.ncbi.nlm.nih.gov/compound/11497983 NCBI PubChem CID:11497983]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=53927 Hanley et al., 2017]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=53927 Hanley et al., 2017]



Revision as of 08:54, 28 November 2017

Description

Barasertib specifically binds to and inhibits Aurora kinase B, which results in the disruption of spindle checkpoint functions and chromosome alignment and, so, the disruption of chromosome segregation and cytokinesis.

File:?structure.png
? structure, image from PubChem

Alternative names

  • AZD1152
  • UNII-16XC2U7W8N

Suppliers

Usage Notes

References

> 7 Xenbase articles contain a reference to Barasertib or AZD1152 according to textpresso