Barasertib: Difference between revisions
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Barasertib specifically binds to and inhibits Aurora kinase B, which results in the disruption of spindle checkpoint functions and chromosome alignment and, so, the disruption of chromosome segregation and cytokinesis. | Barasertib specifically binds to and inhibits Aurora kinase B, which results in the disruption of spindle checkpoint functions and chromosome alignment and, so, the disruption of chromosome segregation and cytokinesis. | ||
[[File: | [[File:Barasertib.png|frame|right|Barasertib structure, image from PubChem]] | ||
==Alternative names== | ==Alternative names== | ||
Revision as of 08:55, 28 November 2017
Description
Barasertib specifically binds to and inhibits Aurora kinase B, which results in the disruption of spindle checkpoint functions and chromosome alignment and, so, the disruption of chromosome segregation and cytokinesis.
Alternative names
- AZD1152
- UNII-16XC2U7W8N
Suppliers
Usage Notes
References
> 7 Xenbase articles contain a reference to Barasertib or AZD1152 according to textpresso