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Created page with "= ''cyp46a1.1'' = =gene nomenclature & synteny= There are 3 named ''Xenopus cyp46a1'' genes, a tadem duplication , ''cyp46a1.1, cyp46a1.2, cyp46a1.3'', all on chr8 [Chr8:90..." |
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=gene nomenclature & synteny= | =gene nomenclature & synteny= | ||
There are 3 named ''Xenopus cyp46a1'' genes, a tadem duplication , ''cyp46a1.1, cyp46a1.2, cyp46a1.3'', all on chr8 [Chr8:90631914..90931414 ], in this gene pattern ''ccdc85c< hhipl1> '''cyp46a1.1 | There are 3 named ''Xenopus cyp46a1'' genes, a tadem duplication , ''cyp46a1.1, cyp46a1.2, cyp46a1.3'', all on chr8 [Chr8:90631914..90931414 ], in this gene pattern ''ccdc85c< hhipl1> '''cyp46a1.1 cyp46a1.2, cyp46a1.3''' mia2> fbxo33<'' | ||
There is another cyp46a1-like gene duplication, also on Chr8, which we are giving the following names: cyp46a1. | There is another cyp46a1-like gene duplication, also on Chr8, which we are giving the following names: cyp46a1.4, cyp46a1.5p (the p suffix as it is a pseudogene) and ''cyp46a1.6'' . | ||
These extra ''cyp46a1-like'' genes, seems to be a duplication of the duplication, and is only seen in the ''X.tropicalis'' and does not appear in Human, mouse or ''X. laevis''. | These extra ''cyp46a1-like'' genes, seems to be a duplication of the duplication, and is only seen in the ''X.tropicalis'' and does not appear in Human, mouse or ''X. laevis''. | ||
Revision as of 09:52, 17 April 2023
cyp46a1.1
gene nomenclature & synteny
There are 3 named Xenopus cyp46a1 genes, a tadem duplication , cyp46a1.1, cyp46a1.2, cyp46a1.3, all on chr8 [Chr8:90631914..90931414 ], in this gene pattern ccdc85c< hhipl1> cyp46a1.1 cyp46a1.2, cyp46a1.3 mia2> fbxo33<
There is another cyp46a1-like gene duplication, also on Chr8, which we are giving the following names: cyp46a1.4, cyp46a1.5p (the p suffix as it is a pseudogene) and cyp46a1.6 .
These extra cyp46a1-like genes, seems to be a duplication of the duplication, and is only seen in the X.tropicalis and does not appear in Human, mouse or X. laevis.
synteny patterns:
Xtrop.Chr8:85600001..86207500 (607.5 Kb): spata7> ptpn21< zc3h14> eml5< ttc8> LOC100498621|ch24h/cyp46a1> LOC105948085[unch-pseudo]> LOC100145328|cyp46a1-like> foxn3< efcab11< tdp1>
Xla.chr8L: spata7.L> ptpn21.L< zc3h14.L> LOC108698703|eml5< ttc8.L> [ no duplicated cyp46a1 genes ] foxn3.L<
Xla.Chr8S: foxn3.S> LOC108699830|eml5> zc3h14.S< ptpn21.S> kcnk10.S> gpr65.S<
Human: EML5< TTC8< [LOTS OF ENHANCERS] FOXN3< EFCAB11< TDP1> KCNH13>
MouseChr12: Spata7> Ptpn21< Zc3h14> EML5< TTC8<