XB-FEAT-950176: Difference between revisions

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This is the community wiki page for the gene ''atp2b4'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.
This is the community wiki page for the gene ''atp2b4'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.


=gene annotation and nomenclature changes=
=gene annotation corrections=


19APRIL2023
19APRIL2023
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The gene names and designations for ''atp2b2'' and ''atp2b4'' have been reassessed.
The gene names and designations for ''atp2b2'' and ''atp2b4'' have been reassessed.


Based on Synteny with human, it appears these genes in ''Xenopus'' had been mis-labelled, and corrected here.


Based on Synteny with human, it appears these genes in ''Xenopus'' had been mis-labelled, and are corrected here.
''Xenopus at2b2'' genes are on Chr4/4L4S, and do not share the same flanking genes as is present in mammals.
 
''Xenopus at2b2'' genes are on Chr4/4L4S, and do not share the same immediate flanking genes as in mammals, but a commonality is seen across human frog and fish.




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XtropChr4:  ''aspn> omd> ogn> nol8> iars1> '''atp2b2'''> fancd2>''  
XtropChr4:  ''aspn> omd> ogn> nol8> iars1> '''atp2b2'''> fancd2>''  


Xla.chr4L: ''ogn.l> nol8.L>  iars1.L> '''atp2b2.L>'''  fancd2.L>  fancd2os.L<  fancd2os<''
Xla.Lchr4L: ''ogn.l> nol8.L>  iars1.L> '''atp2b2.L>'''  fancd2.L>  fancd2os.L<  fancd2os<''


Xla.chr4S: ''aspn.S> LOC> ogn.S> iars1.S> '''atp2b2.S>''' bsn.S<  dag1.S> usp4.S>''
Zfish. chr17: rpl29> iars1> '''atp2b2'''> slca11b> slc6a1b> atg7>  


Zfish: rpl29> iars1> '''atp2b2'''> slca11b> slc6a1b> atg7>


''Xenopus'' ''atp2b4'' genes are on Chr2/2S ( not present on Xlaevis 2L) and share a conserved synteic gene patern with mammals, and lesser extent fish. These are the true orthologs of human ATP2B4.


''Xenopus'' ''atp2b4'' genes are on Chr2/2S (not present on Xlaevis 2L in the v10 genome annotation) and share a conserved syntenic gene pattern with mammals, andto a lesser extent, fish.


These are the true orthologs of human ATP2B4.
HUMANCHR1:  FMOD< PRELP> OPTC> '''ATP2B4'''> LAX1>  ZC3H11A/ZBED6>  SNRPE>


XtropChr2: ''srpk1< mapk14>  zc3h11a<  '''LOC100488346|atp2b4<'''  optc<  prelp< fmod>''


''Xenopus at2b2'' genes are on Chr4/4L4S, and do not share the same immediate flanking genes as in mammals, but a commonality is seen across human frog and fish.
Xla.chr2S: ''srpk1.S<  mapk14.S>  zc3h11a.S<  '''LOC108709452|atp2b4<'''  optc.S<  prelp.S< fmod.S>''


Zfish.chr11: kiss1> csf1a< optc> '''atp2b4'''>  mdm4> LOC< myog> ppfia4<


HumanCHR3:  GHRLOS> GHRL< SEC13< '''ATP2B2'''< SLC6A1> SLC6A11> HRH1>
=nomenclature changes=
 
19APRIL2023
XtropChr4:  ''aspn> omd> ogn> nol8> iars1> '''atp2b2'''> fancd2>''
 
Xla.chr4L: ''ogn.l> nol8.L>  iars1.L> '''atp2b2.L>'''  fancd2.L>  fancd2os.L<  fancd2os<''


Xla.chr4S: ''aspn.S> LOC> ogn.S> iars1.S> '''atp2b2.S>''' bsn.S<  dag1.S> usp4.S>''
X. tropicalis Gene ID 100488346  [XB-GENE-950177] change from atp2b2, ATPase, Ca++ transporting, plasma membrane 2 to atp2b4, ATPase plasma membrane Ca2+ transporting 4


Zfish: rpl29> iars1> '''atp2b2'''> slca11b> slc6a1b> atg7>
X. laevis Gene ID 108709452 [XELAEV_18014870mg] change from LOC108709452, plasma membrane calcium-transporting ATPase 4 to atp2b4.S, ATPase plasma membrane Ca2+ transporting 4 S homeolog


X. tropicalis Gene ID: 100487776 [XB-GENE-960658] change from atp2b4, ATPase, Ca++ transporting, plasma membrane 4 to atp2b2, ATPase plasma membrane Ca2+ transporting 2


''Xenopus'' ''atp2b4'' genes are on Chr2/2S (not present on Xlaevis 2L in the v10 genome annotation) and share a conserved syntenic gene pattern with mammals, andto a lesser extent, fish.  
X. laevis Gene ID: 446855 [XELAEV_18023767mg] change from atp2b4.L, ATPase, Ca++ transporting, plasma membrane 4 L homeolog to atp2b2.L,  ATPase plasma membrane Ca2+ transporting 2 L homeolog


These are the true orthologs of human ATP2B4.
X. laevis Gene ID: 108715812 [XELAEV_18025751mg] change from atp2b4.S, ATPase, Ca++ transporting, plasma membrane 4 S homeolog to atp2b2.S, ATPase plasma membrane Ca2+ transporting 2 S homeolog

Revision as of 08:02, 19 April 2023

atp2b4

This is the community wiki page for the gene atp2b4 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

gene annotation corrections

19APRIL2023

The gene names and designations for atp2b2 and atp2b4 have been reassessed.

Based on Synteny with human, it appears these genes in Xenopus had been mis-labelled, and corrected here.

Xenopus at2b2 genes are on Chr4/4L4S, and do not share the same flanking genes as is present in mammals.


HumanCHR3: GHRLOS> GHRL< SEC13< ATP2B2< SLC6A1> SLC6A11> HRH1>

XtropChr4: aspn> omd> ogn> nol8> iars1> atp2b2> fancd2>

Xla.Lchr4L: ogn.l> nol8.L> iars1.L> atp2b2.L> fancd2.L> fancd2os.L< fancd2os<

Zfish. chr17: rpl29> iars1> atp2b2> slca11b> slc6a1b> atg7>


Xenopus atp2b4 genes are on Chr2/2S ( not present on Xlaevis 2L) and share a conserved synteic gene patern with mammals, and lesser extent fish. These are the true orthologs of human ATP2B4.


HUMANCHR1: FMOD< PRELP> OPTC> ATP2B4> LAX1> ZC3H11A/ZBED6> SNRPE>

XtropChr2: srpk1< mapk14> zc3h11a< LOC100488346|atp2b4< optc< prelp< fmod>

Xla.chr2S: srpk1.S< mapk14.S> zc3h11a.S< LOC108709452|atp2b4< optc.S< prelp.S< fmod.S>

Zfish.chr11: kiss1> csf1a< optc> atp2b4> mdm4> LOC< myog> ppfia4<

nomenclature changes

19APRIL2023

X. tropicalis Gene ID 100488346 [XB-GENE-950177] change from atp2b2, ATPase, Ca++ transporting, plasma membrane 2 to atp2b4, ATPase plasma membrane Ca2+ transporting 4

X. laevis Gene ID 108709452 [XELAEV_18014870mg] change from LOC108709452, plasma membrane calcium-transporting ATPase 4 to atp2b4.S, ATPase plasma membrane Ca2+ transporting 4 S homeolog

X. tropicalis Gene ID: 100487776 [XB-GENE-960658] change from atp2b4, ATPase, Ca++ transporting, plasma membrane 4 to atp2b2, ATPase plasma membrane Ca2+ transporting 2

X. laevis Gene ID: 446855 [XELAEV_18023767mg] change from atp2b4.L, ATPase, Ca++ transporting, plasma membrane 4 L homeolog to atp2b2.L, ATPase plasma membrane Ca2+ transporting 2 L homeolog

X. laevis Gene ID: 108715812 [XELAEV_18025751mg] change from atp2b4.S, ATPase, Ca++ transporting, plasma membrane 4 S homeolog to atp2b2.S, ATPase plasma membrane Ca2+ transporting 2 S homeolog